Orsel Karin, Bouma Annemarie
Department of Production Animal Health, University of Calgary, Alberta, Canada.
Can Vet J. 2009 Oct;50(10):1059-63.
Vaccination against foot-and-mouth disease (FMD) might be one of the control measures used during an FMD epidemic depending on the local epidemiological situation, the status of the country, and the opinion of policy makers. A sound decision on vaccination can be made only if there is sufficient scientific knowledge on the effectiveness of vaccination in eliminating the virus from the population. An important question is whether a single vaccination applied as an emergency vaccine can contribute to the control of an epidemic. This paper presents the results of transmission experiments on vaccine efficacy in groups of cattle, pigs, and sheep and concludes that vaccination seemed to be effective in cattle and sheep, but was less effective in pigs. The possible implications for application to field conditions are discussed.
根据当地的流行病学情况、国家状况以及政策制定者的意见,口蹄疫(FMD)疫苗接种可能是口蹄疫疫情期间采取的控制措施之一。只有在对疫苗接种在从群体中消除病毒的有效性有足够科学认识的情况下,才能做出关于疫苗接种的明智决策。一个重要问题是,作为应急疫苗进行的单次接种是否有助于控制疫情。本文介绍了在牛、猪和羊群体中进行的疫苗效力传播实验结果,并得出结论:疫苗接种在牛和羊中似乎有效,但在猪中效果较差。文中还讨论了应用于实际情况时可能产生的影响。