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新型药物递送系统中的草药辅料。

Herbal excipients in novel drug delivery systems.

作者信息

Shirwaikar A, Shirwaikar Annie, Prabu S Lakshmana, Kumar G Aravind

出版信息

Indian J Pharm Sci. 2008 Jul-Aug;70(4):415-22. doi: 10.4103/0250-474X.44587.

Abstract

The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.

摘要

使用天然辅料来递送生物活性剂受到了合成材料的阻碍。然而,这些天然辅料具有无毒、成本较低且易于获取的优点。辅料的性能在一定程度上决定了药品的质量。辅料作为除活性物质之外的任何成分这一传统概念,已从一种惰性且廉价的载体经历了重大演变,成为制剂的重要组成部分。辅料是指在剂型配方中有意添加的除活性物质之外的任何成分。本文概述了用于传统剂型以及新型药物递送系统的草药辅料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e14/2792536/211959db03dd/IJPhS-70-415-g001.jpg

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