天然聚合物、树胶和黏液质作为药物递送中的辅料。

Natural polymers, gums and mucilages as excipients in drug delivery.

作者信息

Kumar Shobhit, Gupta Satish Kumar

机构信息

Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology Delhi-Roorkee Highway, NH-58, Baghpat Crossing, Meerut-250005, UP India.

出版信息

Polim Med. 2012;42(3-4):191-7.

PMID:23457960

Abstract

Use of natural polymers, gums and mucilages in drug delivery systems has been weighed down by the synthetic materials. Natural based excipients offered advantages such as non-toxicity, less cost and abundantly availablity. Aqueous solubility of natural excipients plays an important role in their selection for designing immediate, controlled or sustained release formulations. This review article provide an overview of natural gum, polymers and mucilages as excipients in dosage forms as well as novel drug delivery systems.

摘要

在药物递送系统中，天然聚合物、树胶和黏液质的应用一直受到合成材料的压制。基于天然的辅料具有诸如无毒、成本较低和易于获得等优点。天然辅料的水溶性在选择用于设计速释、控释或缓释制剂时起着重要作用。这篇综述文章概述了天然树胶、聚合物和黏液质作为剂型以及新型药物递送系统中的辅料的情况。