β-内酰胺酶由模仿葡萄球菌溶葡萄球菌生物变种中的质粒pACK3编码。
Beta-lactamase is encoded on plasmid pACK3 in Staphylococcus simulans biovar staphylolyticus.
作者信息
Heath H E, Heath L S, Rose K E, Sloan G L
机构信息
Department of Microbiology, University of Alabama, Tuscaloosa 35487.
出版信息
FEMS Microbiol Lett. 1991 Jan 1;61(1):113-6. doi: 10.1016/0378-1097(91)90023-4.
PMID:2004692
Abstract
Staphylococcus simulans biovar staphylolyticus, the lysostaphin-producing organism, contains five plasmids designated pACK1 through pACK5. Hybridization analysis using cloned beta-lactamase gene (bla) as probe and characterization of cured strains revealed that bla resides on pACK3 rather than on the lysostaphin endopeptidase plasmid (pACK1) as reported by others.
摘要
产溶葡萄球菌素的模仿葡萄球菌生物变种溶葡萄球菌含有五个质粒，分别命名为pACK1至pACK5。以克隆的β-内酰胺酶基因（bla）为探针进行杂交分析以及对治愈菌株的特性分析表明，bla位于pACK3上，而不像其他人报道的那样位于溶葡萄球菌素内肽酶质粒（pACK1）上。
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