模仿葡萄球菌溶菌生物变种无质粒衍生物的细胞外蛋白质产生特性。

Characteristics of extracellular protein production by a plasmidless derivative of Staphylococcus simulans biovar staphylolyticus.

作者信息

Nitterauer J D, Heath H E, Heath L S, LeBlanc P A, Sloan G L

机构信息

Department of Microbiology, University of Alabama, Tuscaloosa 35487.

出版信息

FEMS Microbiol Lett. 1991 Nov 1;68(1):23-6. doi: 10.1016/0378-1097(91)90388-q.

DOI:10.1016/0378-1097(91)90388-q

PMID:1769550

Abstract

A derivative of Staphylococcus simulans biovar staphylolyticus cured of all five plasmids present in the wild-type organism was developed, and the characteristics of extracellular protein production by this plasmidless strain were compared to those of the wild type. Although staphylolytic endopeptidase (lysostaphin) and beta-lactamase are known to be plasmid encoded, analysis of this cured strain revealed that most other extracellular proteins are chromosomally encoded.

摘要

开发出了一株去除了野生型菌株中所有5种质粒的模仿葡萄球菌溶葡萄球菌生物变种的衍生物，并将该无质粒菌株产生细胞外蛋白的特性与野生型菌株进行了比较。尽管已知溶葡萄球菌内肽酶（溶葡萄球菌素）和β-内酰胺酶是由质粒编码的，但对该去除质粒的菌株的分析表明，大多数其他细胞外蛋白是由染色体编码的。