Mapping of the gene for human cysteine proteinase inhibitor stefin A, STF1, to chromosome 3cen-q21.
作者信息
Hsieh W T, Fong D, Sloane B F, Golembieski W, Smith D I
机构信息
Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
出版信息
Genomics. 1991 Jan;9(1):207-9. doi: 10.1016/0888-7543(91)90241-6.
PMID:2004763
Abstract
The gene for the human cysteine proteinase inhibitor stefin A (STF1), alias cystatin A, has been mapped to chromosome 3, using the polymerase chain reaction to specifically amplify the human stefin A sequence in human-hamster hybrid DNA. STF1 is further sublocalized to regions between centromere and 3q21 using a deletion mapping panel for this chromosome. This assignment shows that stefin A is not syntenic with cystatin C which has been localized to chromosome 20.
摘要
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