School of Population Health, University of Queensland, Brisbane, Queensland, Australia.
Fertil Steril. 2010 Oct;94(5):1817-21. doi: 10.1016/j.fertnstert.2009.10.062. Epub 2010 Jan 4.
To investigate the mental and general health of infertile women who had not sought medical advice for their recognized infertility and were therefore not represented in clinical populations.
Longitudinal cohort study.
Population based.
PATIENT(S): Participants in the Australian Longitudinal Study on Women's Health aged 28-33 years in 2006 who had ever tried to conceive or had been pregnant (n = 5,936).
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Infertility, not seeking medical advice.
RESULT(S): Compared with fertile women (n = 4,905), infertile women (n = 1,031) had higher odds of self-reported depression (odds ratio [OR] 1.20, 95% confidence interval [CI] 1.01-1.43), endometriosis (5.43, 4.01-7.36), polycystic ovary syndrome (9.52, 7.30-12.41), irregular periods (1.99, 1.68-2.36), type II diabetes (4.70, 1.79-12.37), or gestational diabetes (1.66, 1.12-2.46). Compared with infertile women who sought medical advice (n = 728), those who had not sought medical advice (n = 303) had higher odds of self-reported depression (1.67, 1.18-2.37), other mental health problems (3.14, 1.14-8.64), urinary tract infections (1.67, 1.12-2.49), heavy periods (1.63, 1.16-2.29), or a cancer diagnosis (11.33, 2.57-49.89). Infertile women who had or had not sought medical advice had similar odds of reporting an anxiety disorder or anxiety-related symptoms.
CONCLUSION(S): Women with self-reported depression were unlikely to have sought medical advice for infertility. Depression and depressive symptoms may be barriers to seeking medical advice for infertility.
调查未因已知不孕而寻求医疗建议的不孕女性的心理和一般健康状况,这些女性未出现在临床人群中。
纵向队列研究。
基于人群。
2006 年参加澳大利亚妇女健康纵向研究时年龄在 28-33 岁、曾尝试怀孕或已怀孕的参与者(n=5936)。
无。
不孕,未寻求医疗建议。
与生育女性(n=4905)相比,不孕女性(n=1031)报告抑郁的可能性更高(优势比[OR]1.20,95%置信区间[CI]1.01-1.43)、子宫内膜异位症(5.43,4.01-7.36)、多囊卵巢综合征(9.52,7.30-12.41)、月经不规律(1.99,1.68-2.36)、2 型糖尿病(4.70,1.79-12.37)或妊娠期糖尿病(1.66,1.12-2.46)。与寻求医疗建议的不孕女性(n=728)相比,未寻求医疗建议的不孕女性(n=303)报告抑郁(1.67,1.18-2.37)、其他心理健康问题(3.14,1.14-8.64)、尿路感染(1.67,1.12-2.49)、月经过多(1.63,1.16-2.29)或癌症诊断(11.33,2.57-49.89)的可能性更高。有或没有寻求医疗建议的不孕女性报告焦虑症或焦虑相关症状的可能性相似。
报告抑郁的女性不太可能因不孕寻求医疗建议。抑郁和抑郁症状可能是寻求不孕医疗建议的障碍。