Effect of challenge with Candida albicans strains with different levels of virulence on plasma proteins in burned mice.
作者信息
Neely A N, Childress C M, Holder I A
机构信息
Shriners Burns Institute, Cincinnati, Ohio.
出版信息
Infect Immun. 1991 Apr;59(4):1576-8. doi: 10.1128/iai.59.4.1576-1578.1991.
Abstract
Immunoglobulin G, immunoglobulin A, transferrin, and fibrinogen were measured by radial immunodiffusion in plasma samples from burned versus unburned mice challenged with high-virulence Candida albicans MY 1044 or its low-virulence mutant, MY 1049. Early decreases in these proteins were found after burn and/or MY 1044 but not MY 1049 challenge. These decreases may contribute to increased susceptibility of mice that were burned and challenged by MY 1044 to lethal candidiasis.
摘要
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