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Effect of challenge with Candida albicans strains with different levels of virulence on plasma proteins in burned mice.用不同毒力水平的白色念珠菌菌株攻击对烧伤小鼠血浆蛋白的影响。
Infect Immun. 1991 Apr;59(4):1576-8. doi: 10.1128/iai.59.4.1576-1578.1991.
2
Effect of proteolytic activity on virulence of Candida albicans in burned mice.蛋白水解活性对烧伤小鼠白色念珠菌毒力的影响。
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Candida albicans growth studies: a hypothesis for the pathogenesis of Candida infections in burns.
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4
Effects of immunoglobulin G and low-dose amphotericin B on Candida albicans infections in burned mice.免疫球蛋白G和低剂量两性霉素B对烧伤小鼠白色念珠菌感染的影响。
Antimicrob Agents Chemother. 1992 Mar;36(3):643-6. doi: 10.1128/AAC.36.3.643.
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Increased susceptibility to lethal Candida infections in burned mice preinfected with Pseudomonas aeruginosa or pretreated with proteolytic enzymes.预先感染铜绿假单胞菌或用蛋白水解酶预处理的烧伤小鼠对致死性念珠菌感染的易感性增加。
Infect Immun. 1986 Apr;52(1):200-4. doi: 10.1128/iai.52.1.200-204.1986.
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Pathogenicity in mice of strains of Candida albicans (Robin) Berk. isolated from burn patients.从烧伤患者中分离出的白色念珠菌（罗宾）伯克菌株对小鼠的致病性。
Mycopathol Mycol Appl. 1973 Apr 30;49(4):283-8. doi: 10.1007/BF02050722.
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Candida albicans strain-dependent virulence and Rim13p-mediated filamentation in experimental keratomycosis.白色念珠菌菌株依赖性毒力及Rim13p介导的实验性角膜真菌病中的菌丝形成
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Comparative virulence of Candida auris with Candida haemulonii, Candida glabrata and Candida albicans in a murine model.在小鼠模型中比较耳念珠菌、近平滑念珠菌、光滑念珠菌和白色念珠菌的毒力。
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引用本文的文献

1
Cell wall and secreted proteins of Candida albicans: identification, function, and expression.白色念珠菌的细胞壁和分泌蛋白：鉴定、功能及表达
Microbiol Mol Biol Rev. 1998 Mar;62(1):130-80. doi: 10.1128/MMBR.62.1.130-180.1998.
2
Effects of immunoglobulin G and low-dose amphotericin B on Candida albicans infections in burned mice.免疫球蛋白G和低剂量两性霉素B对烧伤小鼠白色念珠菌感染的影响。
Antimicrob Agents Chemother. 1992 Mar;36(3):643-6. doi: 10.1128/AAC.36.3.643.

本文引用的文献

1
Changes in acute phase reactants and disturbances in metabolism after burn injury.烧伤后急性期反应物的变化及代谢紊乱
Burns Incl Therm Inj. 1983 Mar;9(4):234-9. doi: 10.1016/0305-4179(83)90052-9.
2
Comparative pathogenicity of auxotrophic mutants of Candida albicans.白色念珠菌营养缺陷型突变体的致病性比较
Can J Microbiol. 1984 Jan;30(1):31-5. doi: 10.1139/m84-005.
3
Studies on pathological plasma proteolysis in severely burned patients using chromogenic peptide substrate assays: a preliminary report.使用生色肽底物分析法对重度烧伤患者病理性血浆蛋白水解的研究：初步报告。
Adv Exp Med Biol. 1984;167:449-54. doi: 10.1007/978-1-4615-9355-3_39.
4
Elevated serum iron, low unbound transferrin and candidiasis in acute leukemia.急性白血病患者血清铁升高、未结合转铁蛋白降低及念珠菌感染。
Blood. 1969 Oct;34(4):441-51.
5
Immunochemical quantitation of antigens by single radial immunodiffusion.通过单向辐射免疫扩散法对抗原进行免疫化学定量。
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
6
Phagocytosis by human monocytes.人类单核细胞的吞噬作用。
Blood. 1968 Sep;32(3):423-35.
7
Serum protein profiles in thermal burns. I. Serum electrophoretic patterns, immunoglobulins, and transport proteins.热烧伤患者的血清蛋白谱。I. 血清电泳图谱、免疫球蛋白和转运蛋白。
J Trauma. 1974 Feb;14(2):137-52.
8
Early activation of humoral proteolytic systems in patients with multiple trauma.多发伤患者体液蛋白水解系统的早期激活
Crit Care Med. 1986 Nov;14(11):917-25. doi: 10.1097/00003246-198611000-00001.
9
Fungal sepsis: an increasing problem in major thermal injuries.真菌性败血症：重大热损伤中日益严重的问题。
J Burn Care Rehabil. 1986 Nov-Dec;7(6):488-91.
10
Comparison of the extracellular proteinase activity produced by a low-virulence mutant of Candida albicans and its wild-type parent.白色念珠菌低毒力突变体与其野生型亲本产生的细胞外蛋白酶活性比较。
Infect Immun. 1988 May;56(5):1388-90. doi: 10.1128/iai.56.5.1388-1390.1988.

用不同毒力水平的白色念珠菌菌株攻击对烧伤小鼠血浆蛋白的影响。

Effect of challenge with Candida albicans strains with different levels of virulence on plasma proteins in burned mice.

作者信息

Neely A N, Childress C M, Holder I A

机构信息

Shriners Burns Institute, Cincinnati, Ohio.

出版信息

Infect Immun. 1991 Apr;59(4):1576-8. doi: 10.1128/iai.59.4.1576-1578.1991.

DOI:10.1128/iai.59.4.1576-1578.1991
PMID:2004833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC257881/
Abstract

Immunoglobulin G, immunoglobulin A, transferrin, and fibrinogen were measured by radial immunodiffusion in plasma samples from burned versus unburned mice challenged with high-virulence Candida albicans MY 1044 or its low-virulence mutant, MY 1049. Early decreases in these proteins were found after burn and/or MY 1044 but not MY 1049 challenge. These decreases may contribute to increased susceptibility of mice that were burned and challenged by MY 1044 to lethal candidiasis.

摘要

通过放射免疫扩散法，对遭受高毒力白色念珠菌MY 1044或其低毒力突变体MY 1049攻击的烧伤小鼠和未烧伤小鼠的血浆样本中的免疫球蛋白G、免疫球蛋白A、转铁蛋白和纤维蛋白原进行了测定。在烧伤和/或遭受MY 1044攻击后，发现这些蛋白质早期减少，但遭受MY 1049攻击后未出现这种情况。这些减少可能导致遭受烧伤并受到MY 1044攻击的小鼠对致命性念珠菌病的易感性增加。