Andermann A, Blancquaert I, Beauchamp S, Costea I
McGill University, Montreal, Que., Canada.
Public Health Genomics. 2011;14(1):9-16. doi: 10.1159/000272898. Epub 2009 Dec 29.
With the ever-widening gap between what is technologically possible and services available, jurisdictions around the world are faced with complex decisions regarding the introduction and expansion of genetic screening programs. A series of literature reviews and consultations with stakeholders and experts led to the development of a decision support guide for genetic screening policy-making. This involved establishing a preliminary list of core criteria synthesized from the growing literature on genetic screening, which was then transformed through a series of consultations into a more elaborate decision guide. Although certain perennial challenges in genetic screening policy-making remain, the decision support guide aims to promote a fair and evidence-informed process that makes explicit the ethical dilemmas often inherent to such policy decisions.
随着技术上可行的事物与可得的服务之间的差距不断扩大，世界各地的司法管辖区在引入和扩大基因筛查项目方面面临着复杂的决策。一系列的文献综述以及与利益相关者和专家的磋商促成了一份基因筛查政策制定决策支持指南的制定。这包括根据关于基因筛查的不断增多的文献建立一份核心标准初步清单，然后通过一系列磋商将其转化为一份更详尽的决策指南。尽管基因筛查政策制定中某些长期存在的挑战依然存在，但该决策支持指南旨在推动一个公平且基于证据的过程，明确此类政策决策中常常固有的伦理困境。
