Princeton University, Princeton, NJ 08544, USA.
J Health Serv Res Policy. 2010 Apr;15(2):90-7. doi: 10.1258/jhsrp.2009.009084. Epub 2010 Feb 22.
Policy-makers are faced with increasing pressures from a range of different stakeholders to introduce or expand genetic screening programmes. A shared understanding is therefore needed of the many factors influencing these complex policy decisions. Our aim was to develop a theoretical framework that highlights the multiple components and influences involved in genetic screening and the policy-making process.
As part of a larger research programme, existing policy frameworks relating to genetic screening were identified through a review of the literature. Major themes were identified and synthesized into an overarching framework, which was further refined through discussions with key informants.
The framework consists of three parts. The first part conceptualizes genetic screening as an integrated public health programme. The second part describes the policy-making process at each stage in the life cycle of the programme. The third part depicts the broader context within which policy-making occurs.
This framework can support policy-makers by fostering a common understanding and facilitating dialogue with stakeholders. The framework has also been used as the conceptual foundation for the development of a more elaborate decision-guide.
政策制定者面临着来自不同利益相关者的越来越多的压力，需要引入或扩大基因筛查计划。因此，需要对影响这些复杂政策决策的许多因素有一个共同的理解。我们的目的是开发一个理论框架，突出基因筛查和决策过程中涉及的多个组成部分和影响。
作为一个更大的研究计划的一部分，通过文献回顾确定了与基因筛查相关的现有政策框架。确定了主要主题，并将其综合成一个总体框架，通过与主要信息提供者的讨论进一步完善了该框架。
该框架由三部分组成。第一部分将基因筛查概念化为一个综合的公共卫生计划。第二部分描述了该计划生命周期中每个阶段的决策过程。第三部分描述了政策制定发生的更广泛的背景。
该框架可以通过促进共同理解和促进与利益相关者的对话来支持政策制定者。该框架还被用作更详细决策指南的概念基础。
