Cheong Ying, Nardo Luciano G, Rutherford Tony, Ledger William
Division of Developmental Origins of Adult Diseases, University of Southampton School of Medicine (DOHaD), Level F, Princess Anne Hospital, Southampton, UK.
Hum Fertil (Camb). 2010 Mar;13(1):3-12. doi: 10.3109/14647270903438830.
The objectives of this systematic review were to determine the effectiveness of (a) acupuncture and (b) Chinese herbal medicine on the treatment of male and female subfertility by assisted reproductive technologies (ART). All reports from RCTs of acupuncture and/or Chinese herbal medicine in ART were obtained via searches through The Cochrane Menstrual Disorders and Sub-fertility Group's Specialised Register of controlled trials, and other major databases. The outcome measures were determined prior to starting the search, and comprised: live birth rate, ongoing pregnancy rate, clinical pregnancy rate, the incidence of ovarian hyperstimulation syndrome and multiple pregnancy, miscarriage rate and adverse effects arising from treatment. Overall, 14 trials (a total of 2670 subjects) were included in the meta-analysis. The results provided no evidence of benefit in the use of acupuncture during assisted conception. Further studies should attempt to explore the potential placebo, as well as treatment, effects of this complimentary therapy. Essential elements for a quality RCT will be the size of the trial, the use of a standardised acupuncture method and of placebo needles.
本系统评价的目的是确定（a）针灸和（b）中药辅助生殖技术（ART）治疗男性和女性不育症的有效性。通过检索Cochrane月经失调与不育症小组的对照试验专门注册库以及其他主要数据库，获取了关于针灸和/或中药在ART中的所有随机对照试验报告。在开始检索之前确定了结局指标，包括：活产率、持续妊娠率、临床妊娠率、卵巢过度刺激综合征和多胎妊娠的发生率、流产率以及治疗引起的不良反应。总体而言，14项试验（共2670名受试者）纳入了荟萃分析。结果未提供在辅助受孕期间使用针灸有益的证据。进一步的研究应尝试探索这种补充疗法的潜在安慰剂效应以及治疗效果。高质量随机对照试验的基本要素将是试验规模、标准化针灸方法的使用以及安慰剂针的使用。
