Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Bioinformatics. 2010 Mar 1;26(5):700-2. doi: 10.1093/bioinformatics/btp705. Epub 2010 Jan 6.
Biological trace elements are required for numerous biological processes and by all organisms. We describe a database, dbTEU (DataBase of Trace Element Utilization), that features known transporters and user proteins for five trace elements (copper, molybdenum, nickel, cobalt and selenium) and represents sequenced organisms from the three domains of life. The manually curated dbTEU currently includes approximately 16,500 proteins from >700 organisms, and offers interactive trace element, protein, organism and sequence search and browse tools.
dbTEU is freely available at http://gladyshevlab.bwh.harvard.edu/trace_element/
生物微量元素是众多生物过程和所有生物体所必需的。我们描述了一个数据库 dbTEU(微量元素利用数据库),其中包含五个微量元素(铜、钼、镍、钴和硒)的已知转运蛋白和用户蛋白,代表了来自生命三个域的测序生物。目前,经过人工整理的 dbTEU 包括来自>700 个生物体的约 16500 种蛋白质,并提供交互式微量元素、蛋白质、生物体和序列搜索和浏览工具。
dbTEU 可免费在 http://gladyshevlab.bwh.harvard.edu/trace_element/ 获得。