Eloy P, Leruth E, Bertrand B, Rombaux P H
ENT and HNS department, Cliniques Universitaires de Mont-Godinne, Université Catholique de Louvain, 5530, Yvoir, Belgium.
Clin Ophthalmol. 2009;3:651-6. doi: 10.2147/opth.s5920. Epub 2009 Dec 29.
Wegener's granulomatosis (WG) is one form of idiopathic autoimmune vasculitis. The disease has a predilection for the upper and lower respiratory tracts (lungs, nose, sinus), and kidneys. WG may be systemic, severe, and potentially lethal, but it may also be limited to the otolaryngological area or to the eyes and the orbits. Obstruction of the lacrimal pathway is a possible complication of the disease that affects approximately 7% of patients with WG. It usually occurs as a direct extension of sinonasal disease and typically is a late manifestation. Management of such a condition is generally viewed as difficult. We report the case of a patient with a quiescent WG limited to the otolaryngological area. This patient presented a bilateral obstruction of the nasolacrimal ducts caused by bilateral extensive adhesions in the nasal cavity. Because she had several episodes of left-side acute dacryocystitis which necessitated several courses of broad-spectrum antibiotics, she successfully underwent an endonasal endoscopic dacryocystorhinostomy using a diode laser and powered instrumentation. The authors describe the clinical case, the surgical technique, and review the literature.
韦格纳肉芽肿(WG)是特发性自身免疫性血管炎的一种形式。该疾病好发于上、下呼吸道(肺、鼻、鼻窦)及肾脏。WG可能是全身性的、严重的且有潜在致死性,但也可能局限于耳鼻喉科区域或眼部及眼眶。泪道阻塞是该疾病的一种可能并发症,约7%的WG患者会受到影响。它通常是鼻窦疾病的直接蔓延,且通常是晚期表现。这种情况的治疗通常被认为很困难。我们报告一例局限于耳鼻喉科区域的静止期WG患者。该患者因鼻腔双侧广泛粘连导致双侧鼻泪管阻塞。由于她多次发生左侧急性泪囊炎,需要使用多个疗程的广谱抗生素,她成功接受了使用二极管激光和动力器械的鼻内镜下泪囊鼻腔造口术。作者描述了该临床病例、手术技术并回顾了相关文献。