University of Minnesota, Minneapolis, MN 55454, USA.
Matern Child Health J. 2011 Feb;15(2):198-204. doi: 10.1007/s10995-009-0558-y.
The main objective of this work is to examine low prenatal mood, alcohol and tobacco use and rates of preterm (PTB) and low birth weight (LBW) births among women in Minnesota between 2002 and 2006. We examined the Minnesota version of the national, cross-sectional survey of postpartum women, the Pregnancy Risk Assessment Monitoring System (MN PRAMS). Of the 11,891 women sampled in 2002-2006, 7,457 had complete data for analysis; the weighted response rates averaged 76%. The major variables of interest were: LBW, PTB, maternal mood during pregnancy, prenatal alcohol use, prenatal tobacco use and interaction terms created from the mood and substance use variables. Women with low mood who used tobacco during pregnancy were twice as likely to have a LBW infant as women who did not smoke and reported high mood (AOR = 2.12, 95% CI: 1.35, 3.33, P = 0.001). Among women who abstained from alcohol during pregnancy, those with low mood were at an increased risk for PTB (AOR = 1.95, 95% CI: 1.54-2.45, P < 0.0001) compared to women with high mood. Low maternal mood was associated with increased risks for PTB, and LBW births among MN PRAMS respondents. Substance use and low prenatal mood co-occur and the combined effect on PTB and LBW birth outcomes warrants further investigation.
本研究旨在调查 2002 年至 2006 年间明尼苏达州女性的低产前情绪、酒精和烟草使用情况，以及早产（PTB）和低出生体重（LBW）的发生率。我们调查了明尼苏达州全国产后妇女横断面调查（MN PRAMS）的版本。在 2002-2006 年抽样的 11891 名女性中，有 7457 名女性具有完整的数据分析资料，加权回复率平均为 76%。主要关注的变量有：LBW、PTB、妊娠期间的母亲情绪、产前酒精使用、产前烟草使用以及情绪和物质使用变量创建的交互项。在怀孕期间吸烟且情绪低落的女性，其婴儿 LBW 的可能性是不吸烟且情绪较高的女性的两倍（AOR=2.12，95%CI：1.35，3.33，P=0.001）。在怀孕期间不饮酒的女性中，情绪低落的女性发生 PTB 的风险增加（AOR=1.95，95%CI：1.54-2.45，P<0.0001），而情绪较高的女性则不然。在 MN PRAMS 受访者中，低产妇情绪与 PTB 和 LBW 出生风险增加有关。物质使用和低产前情绪同时发生，对 PTB 和 LBW 出生结局的综合影响值得进一步研究。
