The role of microRNA-133 in cardiac hypertrophy uncovered.
作者信息
Abdellatif Maha
出版信息
Circ Res. 2010 Jan 8;106(1):16-8. doi: 10.1161/CIRCRESAHA.109.212183.
Abstract
摘要
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本文引用的文献
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MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts.微小 RNA-133a 可预防心肌纤维化并调节电复极化，而不影响压力超负荷成年心脏的肥厚。
Circ Res. 2010 Jan 8;106(1):166-75. doi: 10.1161/CIRCRESAHA.109.202176. Epub 2009 Nov 5.
2
MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer.微小RNA 133B靶向肺癌中的促生存分子MCL-1和BCL2L2。
Biochem Biophys Res Commun. 2009 Oct 23;388(3):483-9. doi: 10.1016/j.bbrc.2009.07.143. Epub 2009 Aug 3.
3
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.miR-199a的下调可解除对缺氧诱导因子-1α和沉默调节蛋白1的抑制，并在心肌细胞中重现缺氧预处理。
Circ Res. 2009 Apr 10;104(7):879-86. doi: 10.1161/CIRCRESAHA.108.193102. Epub 2009 Mar 5.
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miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling.miR-133和miR-30调控结缔组织生长因子：微小RNA在心肌基质重塑中的作用
Circ Res. 2009 Jan 30;104(2):170-8, 6p following 178. doi: 10.1161/CIRCRESAHA.108.182535. Epub 2008 Dec 18.
5
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart.微小RNA-133a调节心肌细胞增殖并抑制心脏中平滑肌基因的表达。
Genes Dev. 2008 Dec 1;22(23):3242-54. doi: 10.1101/gad.1738708. Epub 2008 Nov 17.
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A microRNA signature for a BMP2-induced osteoblast lineage commitment program.一种用于骨形态发生蛋白2诱导的成骨细胞谱系定向程序的微小RNA特征
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Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart.miR-1/miR-133的下调有助于肥厚心脏中起搏通道基因HCN2和HCN4的重新表达。
J Biol Chem. 2008 Jul 18;283(29):20045-52. doi: 10.1074/jbc.M801035200. Epub 2008 May 5.
8
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.小鼠和人类胚胎干细胞中细胞谱系的微小RNA调控
Cell Stem Cell. 2008 Mar 6;2(3):219-29. doi: 10.1016/j.stem.2008.01.016.
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Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish.成纤维细胞生长因子依赖性的微小RNA-133缺失促进斑马鱼附肢再生。
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