Institute for Fluid Mechanics, Karlsruhe Institute of Technology, Kaiserstrasse 10, 76131 Karlsruhe, Germany.
Ann Biomed Eng. 2010 Apr;38(4):1426-41. doi: 10.1007/s10439-009-9895-7. Epub 2010 Jan 8.
We present a 3D code-coupling approach which has been specialized towards cardiovascular blood flow. For the first time, the prescribed geometry movement of the cardiovascular flow model KaHMo (Karlsruhe Heart Model) has been replaced by a myocardial composite model. Deformation is driven by fluid forces and myocardial response, i.e., both its contractile and constitutive behavior. Whereas the arbitrary Lagrangian-Eulerian formulation (ALE) of the Navier-Stokes equations is discretized by finite volumes (FVM), the solid mechanical finite elasticity equations are discretized by a finite element (FEM) approach. Taking advantage of specialized numerical solution strategies for non-matching fluid and solid domain meshes, an iterative data-exchange guarantees the interface equilibrium of the underlying governing equations. The focus of this work is on left-ventricular fluid-structure interaction based on patient-specific magnetic resonance imaging datasets. Multi-physical phenomena are described by temporal visualization and characteristic FSI numbers. The results gained show flow patterns that are in good agreement with previous observations. A deeper understanding of cavity deformation, blood flow, and their vital interaction can help to improve surgical treatment and clinical therapy planning.
我们提出了一种专门针对心血管血流的 3D 代码耦合方法。这是首次用心肌复合模型代替心血管流动模型 KaHMo(卡尔斯鲁厄心脏模型)的规定几何运动。变形由流体力和心肌反应驱动,即其收缩和本构行为。Navier-Stokes 方程的任意拉格朗日-欧拉公式(ALE)通过有限体积(FVM)离散化,固体力学有限弹性方程通过有限元(FEM)方法离散化。利用非匹配流体和固体域网格的专门数值求解策略,迭代数据交换保证了基础控制方程的界面平衡。这项工作的重点是基于患者特定磁共振成像数据集的左心室流固耦合。时变可视化和特征 FSI 数描述了多物理现象。所得结果显示出与先前观察结果一致的流动模式。更深入地了解腔变形、血流及其重要相互作用有助于改善手术治疗和临床治疗计划。