Neopterin in cerebrospinal fluid: a useful marker for diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis.

Suppr

超能文献

作者信息

Nomoto M, Utatsu Y, Soejima Y, Osame M

机构信息

Third Department of Internal Medicine, Kagoshima University School of Medicine, Japan.

出版信息

Neurology. 1991 Mar;41(3):457. doi: 10.1212/wnl.41.3.457.

DOI:10.1212/wnl.41.3.457

PMID:2006023

Abstract

摘要

相似文献

Neopterin in cerebrospinal fluid: a useful marker for diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis.

Neurology. 1991 Mar;41(3):457. doi: 10.1212/wnl.41.3.457.

HTLV-I-associated myelopathy: analysis of 213 patients based on clinical features and laboratory findings.人类嗜T淋巴细胞病毒I型相关脊髓病：基于临床特征和实验室检查结果对213例患者的分析

J Neurovirol. 1995 Mar;1(1):50-61. doi: 10.3109/13550289509111010.

Use of cerebrospinal fluid CXCL10 and neopterin as biomarkers in HTLV-1-associated myelopathy/tropical spastic paraparesis treated with steroids.脑脊液CXCL10和新蝶呤作为生物标志物在接受类固醇治疗的人类嗜T淋巴细胞病毒1型相关脊髓病/热带痉挛性截瘫中的应用

J Neurol Neurosurg Psychiatry. 2020 Mar;91(3):321-323. doi: 10.1136/jnnp-2019-321955. Epub 2019 Oct 29.

Differential patterns of serum biomarkers of immune activation in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis, and adult T-cell leukemia/lymphoma.人类嗜T淋巴细胞病毒I型相关脊髓病/热带痉挛性截瘫及成人T细胞白血病/淋巴瘤中免疫激活血清生物标志物的差异模式。

Cancer Epidemiol Biomarkers Prev. 1996 Sep;5(9):699-704.

Neopterin concentrations in serum and cerebrospinal fluid in HTLV-I infected individuals.人类嗜T淋巴细胞病毒I型（HTLV-I）感染个体血清和脑脊液中的新蝶呤浓度。

J Neurol. 1992 May;239(5):270-2. doi: 10.1007/BF00810351.

Clinical and laboratory features of HTLV-I asymptomatic carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis from the Brazilian Amazon.来自巴西亚马逊地区的人类嗜T淋巴细胞病毒I型（HTLV-I）无症状携带者及HTLV-I相关脊髓病/热带痉挛性截瘫患者的临床和实验室特征

Rev Inst Med Trop Sao Paulo. 2017 Apr 3;59:e5. doi: 10.1590/S1678-9946201759005.

Cerebrospinal fluid neopterin, but not osteopontin, is a valuable biomarker for the treatment response in patients with HTLV-I-associated myelopathy.脑脊液新蝶呤而非骨桥蛋白，是人类嗜T淋巴细胞病毒I型相关脊髓病患者治疗反应的一种有价值的生物标志物。

Intern Med. 2013;52(19):2203-8. doi: 10.2169/internalmedicine.52.0869. Epub 2012 Mar 1.

The effect of HTLV-1 virulence factors (HBZ, Tax, proviral load), HLA class I and plasma neopterin on manifestation of HTLV-1 associated myelopathy tropical spastic paraparesis.人嗜T淋巴细胞病毒1型（HTLV-1）毒力因子（HBZ、Tax、前病毒载量）、人类白细胞抗原I类分子（HLA class I）及血浆新蝶呤对HTLV-1相关脊髓病/热带痉挛性截瘫表现的影响

Virus Res. 2017 Jan 15;228:1-6. doi: 10.1016/j.virusres.2016.11.009. Epub 2016 Nov 12.

Human T lymphotropic virus type I (HTLV-I) proviral load in cerebrospinal fluid: a new criterion for the diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis?脑脊液中人类嗜T淋巴细胞病毒I型（HTLV-I）前病毒载量：作为HTLV-I相关脊髓病/热带痉挛性截瘫诊断的新标准？

J Infect Dis. 2005 Jun 1;191(11):1830-4. doi: 10.1086/429962. Epub 2005 Apr 28.

Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy.人类嗜T淋巴细胞病毒I型（HTLV-I）相关脊髓病加重期脑脊液中HTLV-I感染细胞的积聚。

J Neurovirol. 2008 Oct;14(5):459-63. doi: 10.1080/13550280802178538. Epub 2008 Nov 12.

引用本文的文献

Multicenter, randomized, double-blind, placebo-controlled phase 3 study of mogamulizumab with open-label extension study in a minimum number of patients with human T-cell leukemia virus type-1-associated myelopathy.多中心、随机、双盲、安慰剂对照 3 期研究莫格利珠单抗联合最小数量人类 T 细胞白血病病毒 1 型相关脊髓病患者的开放标签扩展研究。

J Neurol. 2024 Jun;271(6):3471-3485. doi: 10.1007/s00415-024-12239-x. Epub 2024 Mar 2.

Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).人类嗜 T 细胞病毒 1 相关脑脊髓病/热带痉挛性截瘫（HAM/TSP）的免疫病毒学标志物。

Retrovirology. 2019 Nov 29;16(1):35. doi: 10.1186/s12977-019-0499-5.

Cerebrospinal Fluid CXCL10 as a Candidate Surrogate Marker for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.脑脊液CXCL10作为人类嗜T淋巴细胞病毒1型相关脊髓病/热带痉挛性截瘫的候选替代标志物

Front Microbiol. 2019 Sep 11;10:2110. doi: 10.3389/fmicb.2019.02110. eCollection 2019.

The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis.CC 趋化因子配体 (CCL) 1 可被病毒转录激活子 Tax 上调，米诺环素可下调 CCL1：可能对 HTLV-1 相关脊髓病/热带痉挛性截瘫的长期治疗有意义。

Virol J. 2017 Dec 4;14(1):234. doi: 10.1186/s12985-017-0902-6.

Rev Inst Med Trop Sao Paulo. 2017 Apr 3;59:e5. doi: 10.1590/S1678-9946201759005.

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis.脑脊液 CXCL10、CXCL9 和新蝶呤作为 HTLV-1 相关脊髓病/热带痉挛性截瘫的候选预后生物标志物。

PLoS Negl Trop Dis. 2013 Oct 10;7(10):e2479. doi: 10.1371/journal.pntd.0002479. eCollection 2013.

Increased expression of OX40 is associated with progressive disease in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.OX40 的表达增加与 HTLV-1 相关的脊髓病/热带痉挛性截瘫患者的进行性疾病有关。

Retrovirology. 2013 May 7;10:51. doi: 10.1186/1742-4690-10-51.

Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder.在逆转录病毒相关性神经炎症疾病中，存在异常高水平的病毒感染 IFN-γ+CCR4+CD4+CD25+T 细胞。

PLoS One. 2009 Aug 5;4(8):e6517. doi: 10.1371/journal.pone.0006517.

In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).人类嗜T淋巴细胞病毒1型（HTLV-1）的HBZ基因在体内的表达与HTLV-1相关脊髓病/热带痉挛性截瘫（HAM/TSP）中的前病毒载量、炎症标志物及疾病严重程度相关。

Retrovirology. 2009 Feb 19;6:19. doi: 10.1186/1742-4690-6-19.

HTLV-I-associated myelopathy: are ferritin, S100beta protein, or guanine nucleotides CSF markers of disease?

J Neurovirol. 2002 Feb;8(1):64-7. doi: 10.1080/135502802317247839.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验