Department of Dermatology, Ajou University School of Medicine, 5 Wonchon-Dong, Yeongtong-Gu, Suwon, 443-721, South Korea.
Arch Dermatol Res. 2010 May;302(4):295-9. doi: 10.1007/s00403-009-1025-8. Epub 2010 Jan 9.
Psoriasis is a relatively common disorder in children and can be triggered by an upper respiratory tract infection. The aim of this study was to compare the clinical features of psoriasis in children and adult. In addition, we evaluated the relationship between anti-streptolysin O (ASO) titers and the clinical features of psoriasis. A total of 30 childhood psoriasis patients and 30 adult psoriasis patients were evaluated. Childhood psoriasis had a facial predominance when compared with the adult psoriasis. The childhood psoriasis patients with high ASO titers had guttate psoriasis more frequently than patients with normal ASO titers. In children with plaque-type psoriasis, psoriasis area and severity index score was increased in the high ASO titer group than normal ASO titer group. In conclusion, if the children with psoriasis show increased ASO titer, the physician should pay attention to the worsening of the psoriasis. Furthermore, early treatment of streptococcal infections might be beneficial in childhood psoriasis.
银屑病在儿童中较为常见，可由上呼吸道感染诱发。本研究旨在比较儿童和成人银屑病的临床特征。此外，我们评估了抗链球菌溶血素 O（ASO）滴度与银屑病临床特征之间的关系。共评估了 30 例儿童银屑病患者和 30 例成人银屑病患者。与成人银屑病相比，儿童银屑病更易发生于面部。ASO 滴度高的儿童银屑病患者更易出现点滴状银屑病，而 ASO 滴度正常的患者则较少。在斑块型银屑病患儿中，高 ASO 滴度组的银屑病面积和严重程度指数评分高于正常 ASO 滴度组。总之，如果银屑病患儿的 ASO 滴度升高，医生应注意银屑病的恶化。此外，早期治疗链球菌感染可能对儿童银屑病有益。
