Department of Psychology, Temple University, 1701 North 13th Street, Philadelphia, PA 19122, USA.
Child Psychiatry Hum Dev. 2010 Jun;41(3):330-41. doi: 10.1007/s10578-009-0170-9.
Research indicates that depression and anxiety are highly comorbid in youth. Little is known, however, about the clinical and family characteristics of youth with principal anxiety disorders and comorbid depressive diagnoses. The present study examined the demographic, clinical, and family characteristics of 200 anxiety-disordered children and adolescents (aged 7-17) with and without comorbid depressive disorders (major depressive disorder or dysthymic disorder), seeking treatment at a university-based anxiety clinic. All participants met DSM-IV diagnostic criteria for a principal anxiety disorder (generalized anxiety disorder, separation anxiety disorder, or social phobia). Of these, twelve percent (n = 24) also met criteria for a comorbid depressive disorder. Results suggest that anxiety-disordered youth with comorbid depressive disorders (AD-DD) were older at intake, had more severe anxious and depressive symptomatology, and were more impaired than anxiety-disordered youth without comorbid depressive disorders (AD-NDD). AD-DD youth also reported significantly more family dysfunction than AD-NDD youth. Future research should examine how this diagnostic and family profile may impact treatment for AD-DD youth.
研究表明，抑郁和焦虑在年轻人中高度共病。然而，对于主要焦虑障碍和并发抑郁诊断的年轻人的临床和家庭特征知之甚少。本研究调查了 200 名患有和不患有并发抑郁障碍（重性抑郁障碍或心境恶劣障碍）的焦虑障碍儿童和青少年（7-17 岁）的人口统计学、临床和家庭特征，他们在一所大学焦虑诊所接受治疗。所有参与者均符合 DSM-IV 主要焦虑障碍（广泛性焦虑障碍、分离焦虑障碍或社交恐惧症）的诊断标准。其中，12%（n=24）也符合并发抑郁障碍的标准。结果表明，患有并发抑郁障碍的焦虑障碍青年（AD-DD）在摄入时年龄较大，焦虑和抑郁症状更严重，功能障碍更严重。AD-DD 青年也报告了比 AD-NDD 青年更严重的家庭功能障碍。未来的研究应探讨这种诊断和家庭特征如何影响 AD-DD 青年的治疗。
