Center for Cancer Prevention and Detection, National Cancer Center, Madu1-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea.
World J Gastroenterol. 2010 Jan 14;16(2):251-5. doi: 10.3748/wjg.v16.i2.251.
To determine the long-term outcomes regarding reinfection with Helicobacter pylori (H. pylori) and endoscopic changes after successful H. pylori eradication.
From June 1994 to January 2007, 186 patients (M:F = 98:88; mean age 50.0 +/- 11.4 years), in whom H. pylori had been successfully eradicated, were enrolled. The mean duration of follow up was 41.2 +/- 24.0 mo.
H. pylori reinfection occurred in 58 patients (31.2%). The average annual reinfection rate was 9.1% per patient year. No recurrence of peptic ulcer was detected at the follow up endoscopy. There were no significant differences between the H. pylori eradication regimens for the reinfection rate and no significant differences in endoscopic findings between the H. pylori-recurred group and the H. pylori-cured group.
The reinfection rate in Korea is 9.1% which represents a decreasing trend. There was no relationship between H. pylori infection status and changes in endoscopic findings. There was also no recurrence or aggravation of ulcers.
确定成功根除幽门螺杆菌（H. pylori）后再感染和内镜变化的长期结果。
1994 年 6 月至 2007 年 1 月，共纳入 186 例（男：女=98：88；平均年龄 50.0+/-11.4 岁）成功根除 H. pylori 的患者。平均随访时间为 41.2+/-24.0 个月。
58 例（31.2%）患者发生 H. pylori 再感染。每位患者每年的再感染率平均为 9.1%。随访内镜检查未发现消化性溃疡复发。不同的 H. pylori 根除方案之间的再感染率无显著差异，H. pylori 再感染组和 H. pylori 治愈组之间的内镜表现也无显著差异。
韩国的再感染率为 9.1%，呈下降趋势。H. pylori 感染状况与内镜表现变化之间无关系。也没有溃疡的复发或加重。
