构建一个罗托荧光团库，用于开发新型荧光探针。

Construction of a library of rhodol fluorophores for developing new fluorescent probes.

机构信息

Morningside Laboratory for Chemical Biology and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, People's Republic of China.

出版信息

Org Lett. 2010 Feb 5;12(3):496-9. doi: 10.1021/ol902706b.

DOI:10.1021/ol902706b

PMID:20067265

Abstract

A highly efficient and concise synthetic scheme for rhodol fluorophores is developed with palladium-catalyzed amination reaction as the key step. This new synthetic route is utilized to construct a rhodol library, potentially useful for the design of novel fluorescent probes.

摘要

发展了一种高效简洁的若丹明荧光团合成方案，其中钯催化的氨化反应为关键步骤。该新合成路线用于构建若丹明文库，可能对新型荧光探针的设计有用。