Dubut Vincent, Cartault François, Payet Christine, Thionville Marie-Dominique, Murail Pascal
Aix-Marseille Université, CNRS, IRD, UMR 6116-IMEP, Equipe Evolution Génome Environnement, Centre Saint-Charles, Case 36, 3 place Victor Hugo, 13331 Marseille Cedex 3, France.
Hum Biol. 2009 Aug;81(4):495-500. doi: 10.3378/027.081.0407.
Through the sequencing of the complete mitochondrial genome of three individuals of Malagasy ancestry, we completed the characterization of the island southeastern Asian specific M46 haplogroup. We assumed that the association of the np 3588 and np 16278 polymorphisms were M46 specific. In addition, we characterized a novel basal M subhaplogroup: M23. This clade can be defined by one coding region transition at np 10295 and one control region transition at np 16263. Our data suggest the arrival of South Asian migrants before the start of the 15th century and highlights the fact that future studies dealing with the settlement of Madagascar should consider at least three potential source populations (Africa, Indonesia, and India).
通过对三个具有马达加斯加血统个体的完整线粒体基因组进行测序，我们完成了对东南亚岛屿特有的M46单倍群的特征描述。我们假定np 3588和np 16278多态性的关联是M46特有的。此外，我们鉴定出了一个新的基础M亚单倍群：M23。该分支可由np 10295处的一个编码区转换和np 16263处的一个控制区转换来定义。我们的数据表明南亚移民在15世纪初之前就已抵达，并突出了这样一个事实，即未来关于马达加斯加人定居情况的研究应至少考虑三个潜在的源人群体（非洲、印度尼西亚和印度）。
