Arida Ricardo Mario, Scorza Fulvio Alexandre, Terra Vera Cristina, Cysneiros Roberta Monterazzo, Cavalheiro Esper Abrão
Departamento de Fisiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Arq Neuropsiquiatr. 2009 Dec;67(4):1013-6. doi: 10.1590/s0004-282x2009000600010.
People with epilepsy have been discouraged from participating in physical activity due to the fear that it will exacerbate seizures. Clinical and animal studies indicate a reduction of seizure frequency as well as decrease susceptibility to subsequently evoked seizures after an exercise program. Analyses from experimental studies of animals with epilepsy submitted to physical training programs were performed. In all studies the physical training was able to reduce the number of spontaneous seizures in rats with epilepsy. Seizure occurrence during exercise was relatively absent in the majority of studies. No death was found in animals with epilepsy during 1680 h of exercise. Based on these results it is plausible encouraging persons with epilepsy to non-pharmacological treatments and preventative measures such as physical exercise.
由于担心运动会加剧癫痫发作，癫痫患者一直被劝阻不要参加体育活动。临床和动物研究表明，运动计划后癫痫发作频率会降低，并且对随后诱发的癫痫发作的易感性也会降低。对接受体育训练计划的癫痫动物进行了实验研究分析。在所有研究中，体育训练都能够减少癫痫大鼠的自发性癫痫发作次数。在大多数研究中，运动期间相对没有癫痫发作。在1680小时的运动期间，癫痫动物未发现死亡。基于这些结果，鼓励癫痫患者采用非药物治疗和预防措施（如体育锻炼）是合理的。
