Department of Entomology, Michigan State University, East Lansing, MI 48824, USA.
J Econ Entomol. 2009 Dec;102(6):2061-71. doi: 10.1603/029.102.0607.
Direct observations of individual Anopheles gambiae s.s. (Diptera: Culicidae) females fleetingly but repeatedly alighting on pyrethroid-treated fabric of long-lasting insecticide treated nets (LLINs) fitted over a human hand proved that onset of behavioral effects modulated mortality. For Olyset Net, containing 1,000 mg of permethrin per m2, mosquitoes reduced landing attempts and elevated frequency of flight within 3 min. This kinetic disengagement resulted in little mortality. In contrast, mosquito landing attempts on PermaNet (containing 55 mg of deltamethrin per m2) were sustained for up to 6 min before disengagement, and mortality was a frequent outcome. The likely disengagement mechanism was loss of response to host cues, which was restored within 24 h. We conclude that optimal LLIN formulations should maximize engagement so as to maximize mortality.
直接观察到个体冈比亚按蚊（双翅目：蚊科）雌性短暂但反复地降落在经过拟除虫菊酯处理的长效驱虫蚊帐（LLIN）上，证明行为效应的发生调节了死亡率。对于含有 1000 毫克每平方米的氯菊酯的 Olyset 网，蚊子在 3 分钟内减少了降落尝试并增加了飞行频率。这种动力学脱离导致很少的死亡。相比之下，PermaNet（每平方米含有 55 毫克的溴氰菊酯）上的蚊子在脱离之前持续降落尝试长达 6 分钟，且死亡率是常见的结果。可能的脱离机制是失去对宿主线索的反应，这种反应在 24 小时内得到恢复。我们得出结论，最佳的 LLIN 配方应最大限度地提高接触，从而最大限度地提高死亡率。
