人工金属酶的设计策略。
Design strategies for the creation of artificial metalloenzymes.
机构信息
Department of Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland.
出版信息
Curr Opin Chem Biol. 2010 Apr;14(2):184-99. doi: 10.1016/j.cbpa.2009.11.026. Epub 2010 Jan 12.
PMID:20071213
Abstract
In recent years, several complementary strategies have been implemented for the creation and optimization of artificial metalloenzymes. Selected examples outline the pros and cons of five different approaches: catalytic antibodies, computational design, directed evolution, artificial metal-cofactors and DNAzymes.
摘要
近年来，人们已经实施了几种互补策略来创造和优化人工金属酶。选择的例子概述了五种不同方法的优缺点：催化抗体、计算设计、定向进化、人工金属辅因子和 DNA 酶。
Zotero 插件