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Design and engineering of artificial oxygen-activating metalloenzymes.
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Rational Design of Artificial Metalloproteins and Metalloenzymes with Metal Clusters.
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Engineering Metalloprotein Functions in Designed and Native Scaffolds.
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Computational approaches for design and redesign of metal-binding sites on proteins.
Biosci Rep. 2017 Mar 27;37(2). doi: 10.1042/BSR20160179. Print 2017 Apr 28.
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Directed evolution of artificial metalloenzymes for in vivo metathesis.
Nature. 2016 Sep 29;537(7622):661-665. doi: 10.1038/nature19114. Epub 2016 Aug 29.
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Recent achievments in the design and engineering of artificial metalloenzymes.
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Design of functional metalloproteins.
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Application of artificial backbone connectivity in the development of metalloenzyme mimics.
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Design of Artificial Enzymes: Insights into Protein Scaffolds.
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Recent advances in the design and optimization of artificial metalloenzymes.
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Exploring the influence of H-bonding and ligand constraints on thiolate ligated non-heme iron mediated dioxygen activation.
Chem Sci. 2024 Jul 9;15(32):12710-12720. doi: 10.1039/d4sc02787f. eCollection 2024 Aug 14.
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Biohybrid materials comprising an artificial peroxidase and differently shaped gold nanoparticles.
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Artificial Manganese Metalloenzymes with Laccase-like Activity: Design, Synthesis, and Characterization.
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Fresh Impetus in the Chemistry of Calcium Peroxides.
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Heme-copper and Heme O-derived synthetic (bioinorganic) chemistry toward an understanding of cytochrome c oxidase dioxygen chemistry.
J Inorg Biochem. 2023 Dec;249:112367. doi: 10.1016/j.jinorgbio.2023.112367. Epub 2023 Sep 9.
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Selective Oxidation of Halophenols Catalyzed by an Artificial Miniaturized Peroxidase.
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Roles of Metal Ions in Foldamers and Other Conformationally Flexible Supramolecular Systems.
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Ferritin-Like Proteins: A Conserved Core for a Myriad of Enzyme Complexes.
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Isolating Fe-O Intermediates in Dioxygen Activation by Iron Porphyrin Complexes.
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1
Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding.
Chem Sci. 2015 Jul 1;6(7):4060-4065. doi: 10.1039/c5sc01065a. Epub 2015 May 7.
2
Novel artificial metalloenzymes by incorporation of metal-binding unnatural amino acids.
Chem Sci. 2015 Jan 1;6(1):770-776. doi: 10.1039/c4sc01525h. Epub 2014 Oct 9.
3
Artificial Diiron Enzymes with a De Novo Designed Four-Helix Bundle Structure.
Eur J Inorg Chem. 2015 Jul;2015(21):3371-3390. doi: 10.1002/ejic.201500470. Epub 2015 Jul 6.
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Library design and screening protocol for artificial metalloenzymes based on the biotin-streptavidin technology.
Nat Protoc. 2016 May;11(5):835-52. doi: 10.1038/nprot.2016.019. Epub 2016 Mar 31.
6
Chemomimetic biocatalysis: exploiting the synthetic potential of cofactor-dependent enzymes to create new catalysts.
J Am Chem Soc. 2015 Nov 11;137(44):13992-4006. doi: 10.1021/jacs.5b09348. Epub 2015 Nov 3.
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Metalloproteins: Simple structure, complex function.
Nat Chem Biol. 2015 Oct;11(10):760-1. doi: 10.1038/nchembio.1918.
9
A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme.
J Am Chem Soc. 2015 Sep 16;137(36):11570-3. doi: 10.1021/jacs.5b07119. Epub 2015 Sep 8.
10
Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases.
Acc Chem Res. 2015 Sep 15;48(9):2632-9. doi: 10.1021/acs.accounts.5b00312. Epub 2015 Aug 21.

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