Institut für Mikrobiologie und Tierseuchen, Fachbereich für Veterinärmedizin, Freie Universität Berlin, Philippstrasse 13, 10115 Berlin, Germany.
Vet Microbiol. 2010 Jul 29;144(1-2):219-25. doi: 10.1016/j.vetmic.2009.12.016. Epub 2009 Dec 16.
The emergence and spread of multiresistant bacteria in natural environments constitute a serious impact on animal and human health. To gain more insight into the role of wild birds as carriers and reservoir of multiresistant Escherichia coli we tested a broad spectrum of common European bird species for the occurrence of E. coli strains and their antimicrobial resistance by minimal inhibitory concentration testing and PCR analysis of several resistance genes. Nine of the 187 E. coli isolates (4.8%) exhibited multiresistant phenotypes including resistances against beta-lactams, aminoglycosides, fluoroquinolones, tetracyclines and sulfonamides. By comparing avian E. coli resistance frequencies with frequencies known for E. coli isolated from livestock and companion animals analogous profiles were identified. Multiresistant E. coli strains were isolated from synanthropic avian species as well as from birds of prey, waterfowl and passerines. By that, all these avian hosts are suggested to represent a considerable reservoir of resistant E. coli strains. Consequently wild birds might constitute a potential hazard to human and animal health by transmitting multiresistant strains to waterways and other environmental sources via their faecal deposits.
多耐药细菌在自然环境中的出现和传播对动物和人类健康构成了严重威胁。为了更深入地了解野生鸟类作为多耐药大肠杆菌的携带者和储存库的作用，我们通过最小抑菌浓度试验和几种耐药基因的 PCR 分析，测试了广泛的常见欧洲鸟类物种中大肠杆菌菌株的发生情况及其对多种抗生素的耐药性。在 187 株大肠杆菌分离株中，有 9 株（4.8%）表现出多耐药表型，包括对β-内酰胺类、氨基糖苷类、氟喹诺酮类、四环素类和磺胺类的耐药性。通过比较禽源大肠杆菌的耐药频率与从家畜和伴侣动物中分离出的大肠杆菌的耐药频率，发现了类似的模式。多耐药大肠杆菌菌株从栖禽以及猛禽、水禽和雀形目鸟类中分离出来。由此可见，所有这些禽类宿主都可能是耐药大肠杆菌菌株的重要储存库。因此，野生鸟类可能通过其粪便在水道和其他环境源中传播多耐药菌株，对人类和动物健康构成潜在威胁。
