未接受治疗的儿童强迫症的眶额皮质。
Orbital frontal cortex in treatment-naïve pediatric obsessive-compulsive disorder.
机构信息
Department of Psychiatry & Behavioral Neurosciences, Wayne State University, Children's Hospital of Michigan, Detroit, MI 48201, USA.
出版信息
Psychiatry Res. 2010 Feb 28;181(2):97-100. doi: 10.1016/j.pscychresns.2009.08.005. Epub 2010 Jan 13.
Abstract
The orbital frontal cortex (OFC) has been implicated in obsessive-compulsive disorder (OCD). Participants comprised 28 treatment-naïve pediatric OCD patients and 21 controls, who were examined using magnetic resonance imaging. OCD patients had larger right but not left OFC white matter volume than controls. This is fresh evidence implicating white matter in OCD.
摘要
眶额皮层（OFC）与强迫症（OCD）有关。参与者包括 28 名未经治疗的儿科 OCD 患者和 21 名对照，他们接受了磁共振成像检查。OCD 患者的右侧眶额皮层（OFC）白质体积大于左侧，但左侧眶额皮层（OFC）白质体积大于对照组。这是一个新的证据表明，白质在 OCD 中起作用。
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