ENT and Maxillo Surgery Unit, Paris, France.
AJNR Am J Neuroradiol. 2010 Nov;31(10):1967-8. doi: 10.3174/ajnr.A1979. Epub 2010 Jan 14.
HIFU is used in the treatment of cancer (prostate, breast) and uterine fibroma but not yet in TNs. This case report describes the first successful ablation of a toxic TN with HIFU. TSH and radioiodine scan normalization were achieved without complications and maintained for 18 months. HIFU treatment is a minimally invasive technique that may be an effective safe alternative to radioiodine or surgery in patients with toxic TNs.
高强度聚焦超声(HIFU)用于治疗癌症(前列腺、乳腺)和子宫肌瘤,但尚未用于毒性甲状腺结节(TNs)。本病例报告描述了首例成功应用 HIFU 消融治疗毒性 TN。治疗后患者 TSH 和放射性碘扫描恢复正常,且未发生任何并发症,随访 18 个月仍维持该状态。HIFU 治疗是一种微创技术,对于毒性 TN 患者,它可能是放射性碘或手术治疗的有效替代方法,且安全可行。