通过检测尿道拭子和尿液中的抗原对男性衣原体尿道炎进行快速现场诊断。
Rapid, on-site diagnosis of chlamydial urethritis in men by detection of antigens in urethral swabs and urine.
作者信息
Sellors J, Mahony J, Jang D, Pickard L, Castriciano S, Landis S, Stewart I, Seidelman W, Cunningham I, Chernesky M
机构信息
Sexually Transmitted Disease Clinic, Hamilton General Hospital, Ontario, Canada.
出版信息
J Clin Microbiol. 1991 Feb;29(2):407-9. doi: 10.1128/jcm.29.2.407-409.1991.
Abstract
First-void urine (FVU) sediments of 240 men were tested for Chlamydia trachomatis antigens by two enzyme immunoassays, TestPack Chlamydia (15 min) and Chlamydiazyme (3.5 h), and the results were compared with urethral swab culture results. The sensitivity and specificity on FVU sediment for TestPack Chlamydia were 76.2% (32 of 42 specimens) and 95.5% (189 of 198 specimens) versus 81.0% (34 of 42 specimens) and 96.5% (191 of 198 specimens) for Chlamydiazyme, respectively. Rapid, on-site detection of chlamydial antigen in male FVU would shorten the infectious period by hastening diagnosis and treatment.
摘要
采用两种酶免疫测定法，即TestPack衣原体检测法（15分钟）和衣原体酶检测法（3.5小时），对240名男性的首次晨尿（FVU）沉淀物进行沙眼衣原体抗原检测，并将结果与尿道拭子培养结果进行比较。TestPack衣原体检测法对FVU沉淀物的敏感性和特异性分别为76.2%（42个样本中的32个）和95.5%（198个样本中的189个），而衣原体酶检测法的敏感性和特异性分别为81.0%（42个样本中的34个）和96.5%（198个样本中的191个）。对男性FVU中的衣原体抗原进行快速现场检测，将通过加快诊断和治疗来缩短传染期。
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本文引用的文献
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Chlamydia trachomatis infections in the United States. What are they costing us?美国的沙眼衣原体感染。它们让我们付出了怎样的代价？
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Evaluation of a genus-specific monoclonal antibody in an amplified enzyme-linked immunoassay in the detection of Chlamydia in urine samples from men.在一项用于检测男性尿液样本中衣原体的扩增酶联免疫分析中对一种属特异性单克隆抗体的评估。
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