Hevia O, Jimenez-Acosta F, Ceballos P I, Gould E W, Penneys N S
Department of Dermatology and Cutaneous Surgery, University of Miami.
J Am Acad Dermatol. 1991 Feb;24(2 Pt 1):231-5. doi: 10.1016/0190-9622(91)70033-x.
The pruritic papular eruption of the acquired immunodeficiency syndrome is characterized by generalized, pruritic, skin-colored papules and nodules. Chronic lesions are excoriated and hyperpigmented. The eruption and pruritus typically wax and wane and are resistant to oral antihistamine and topical steroid therapy. The characteristic histologic features are (1) superficial and mid dermal perivascular and perifollicular mononuclear cell infiltrate with numerous eosinophils and (2) follicular damage of varying degrees. When compared with control subjects, these patients did not demonstrate any significant difference in laboratory or demographic data.
获得性免疫缺陷综合征的瘙痒性丘疹疹表现为全身性、瘙痒性、肤色丘疹和结节。慢性病变有抓痕和色素沉着。皮疹和瘙痒通常时轻时重，对口服抗组胺药和外用类固醇治疗无效。特征性组织学表现为：（1）真皮浅层和中层血管周围及毛囊周围单核细胞浸润，伴有大量嗜酸性粒细胞；（2）不同程度的毛囊损害。与对照受试者相比，这些患者在实验室检查或人口统计学数据方面没有显示出任何显著差异。
