Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family.
作者信息
Murphy James W, Yuan Hua, Kong Yong, Xiong Yong, Lolis Elias J
机构信息
Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
出版信息
Proteins. 2010 Apr;78(5):1331-7. doi: 10.1002/prot.22666.
Abstract
摘要
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1
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2
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Protein Sci. 2009 Jul;18(7):1359-69. doi: 10.1002/pro.167.
3
Phaser crystallographic software.
J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674. doi: 10.1107/S0021889807021206. Epub 2007 Jul 13.
4
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Sci Signal. 2008 Sep 16;1(37):ra4. doi: 10.1126/scisignal.1160755.
5
Automated structure solution with the PHENIX suite.
Methods Mol Biol. 2008;426:419-35. doi: 10.1007/978-1-60327-058-8_28.
6
Interconversion between two unrelated protein folds in the lymphotactin native state.
Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5057-62. doi: 10.1073/pnas.0709518105. Epub 2008 Mar 25.
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Chemokines and their receptors: drug targets in immunity and inflammation.
Annu Rev Pharmacol Toxicol. 2008;48:171-97. doi: 10.1146/annurev.pharmtox.48.121806.154841.
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Inference of macromolecular assemblies from crystalline state.
J Mol Biol. 2007 Sep 21;372(3):774-97. doi: 10.1016/j.jmb.2007.05.022. Epub 2007 May 13.
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