Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family.
作者信息
Murphy James W, Yuan Hua, Kong Yong, Xiong Yong, Lolis Elias J
机构信息
Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
出版信息
Proteins. 2010 Apr;78(5):1331-7. doi: 10.1002/prot.22666.
Abstract
摘要
相似文献
1
Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family.CXCL12的异源四级结构及其与CC趋化因子家族的关系。
Proteins. 2010 Apr;78(5):1331-7. doi: 10.1002/prot.22666.
2
Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.结构生物学。趋化因子受体CXCR4与一种病毒趋化因子复合物的晶体结构。
Science. 2015 Mar 6;347(6226):1117-22. doi: 10.1126/science.1261064. Epub 2015 Jan 22.
3
Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.人CCL18、CCL3和CCL4的结构揭示了四级结构的分子决定因素以及对胰岛素降解酶的敏感性。
J Mol Biol. 2015 Mar 27;427(6 Pt B):1345-1358. doi: 10.1016/j.jmb.2015.01.012. Epub 2015 Jan 28.
4
Investigation of CC and CXC chemokine quaternary state mutants.CC和CXC趋化因子四级结构突变体的研究
Biochem Biophys Res Commun. 2005 Dec 16;338(2):987-99. doi: 10.1016/j.bbrc.2005.10.062. Epub 2005 Oct 21.
5
Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.G蛋白偶联受体识别趋化因子的结构基础及其对受体激活的影响
Sci Signal. 2017 Mar 21;10(471):eaah5756. doi: 10.1126/scisignal.aah5756.
6
Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences.单体和二聚体状态下趋化因子受体 CXCR4 与其内源性配体 CXCL12 的相互作用：粗粒度模拟鉴定差异。
J Biomol Struct Dyn. 2017 Feb;35(2):399-412. doi: 10.1080/07391102.2016.1145142. Epub 2016 Jul 11.
7
Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype.人CC趋化因子2的溶液结构：CC趋化因子亚型的单体代表物。
Biochemistry. 1999 May 11;38(19):5995-6002. doi: 10.1021/bi990065i.
8
Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine.与CXCL12趋化因子结合的新型小分子配体的结构分析
J Med Chem. 2014 Nov 26;57(22):9693-9. doi: 10.1021/jm501194p. Epub 2014 Nov 13.
9
C-terminal engineering of CXCL12 and CCL5 chemokines: functional characterization by electrophysiological recordings.CXCL12 和 CCL5 趋化因子的 C 末端工程化：通过电生理记录进行功能表征。
PLoS One. 2014 Jan 31;9(1):e87394. doi: 10.1371/journal.pone.0087394. eCollection 2014.
10
The solution structure of the anti-HIV chemokine vMIP-II.抗HIV趋化因子vMIP-II的溶液结构
Protein Sci. 1999 Nov;8(11):2270-80. doi: 10.1110/ps.8.11.2270.
引用本文的文献
1
Structural insights into CXCR4 modulation and oligomerization.对CXCR4调节和寡聚化的结构见解。
Nat Struct Mol Biol. 2025 Feb;32(2):315-325. doi: 10.1038/s41594-024-01397-1. Epub 2024 Sep 23.
2
Interaction and dynamics of chemokine receptor CXCR4 binding with CXCL12 and hBD-3.趋化因子受体CXCR4与CXCL12和人β-防御素3的相互作用及动力学
Commun Chem. 2024 Sep 13;7(1):205. doi: 10.1038/s42004-024-01280-6.
3
C-X-C motif chemokine ligand 12-C-X-C chemokine receptor type 4 signaling axis in cancer and the development of chemotherapeutic molecules.癌症中C-X-C基序趋化因子配体12-C-X-C趋化因子受体4信号轴与化疗分子的研发
Tzu Chi Med J. 2024 May 27;36(3):231-239. doi: 10.4103/tcmj.tcmj_52_24. eCollection 2024 Jul-Sep.
4
Modeling the SDF-1/CXCR4 protein using advanced artificial intelligence and antagonist screening for Japanese anchovy.利用先进人工智能对日本鳀鱼的SDF-1/CXCR4蛋白进行建模及拮抗剂筛选。
Front Physiol. 2024 Feb 2;15:1349119. doi: 10.3389/fphys.2024.1349119. eCollection 2024.
5
Chemokine Heteromers and Their Impact on Cellular Function-A Conceptual Framework.趋化因子异源二聚体及其对细胞功能的影响——概念框架。
Int J Mol Sci. 2023 Jun 30;24(13):10925. doi: 10.3390/ijms241310925.
6
The marriage of chemokines and galectins as functional heterodimers.趋化因子与半乳糖凝集素作为功能异二聚体的联姻。
Cell Mol Life Sci. 2021 Dec;78(24):8073-8095. doi: 10.1007/s00018-021-04010-6. Epub 2021 Nov 12.
7
The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.CXCL13 的 N 端长度和侧链组成影响其结晶、结构和功能活性。
Acta Crystallogr D Struct Biol. 2020 Oct 1;76(Pt 10):1033-1049. doi: 10.1107/S2059798320011687. Epub 2020 Sep 25.
8
High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified : Discovery of a Novel Up-Regulator of CXCR4 Activity.在转基因体系中对功能性人CXCL12-CXCR4信号轴的高通量筛选：CXCR4活性新型上调因子的发现
Front Mol Biosci. 2020 Jul 16;7:164. doi: 10.3389/fmolb.2020.00164. eCollection 2020.
9
Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity.交联引导的完整 CXC 受体-趋化因子复合物的结构及其趋化因子亚家族选择性的基础。
PLoS Biol. 2020 Apr 9;18(4):e3000656. doi: 10.1371/journal.pbio.3000656. eCollection 2020 Apr.
10
Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.鉴定出一个 Arg-Leu-Arg 三肽，该三肽有助于细胞因子 MIF 与趋化因子受体 CXCR4 之间的结合界面。
Sci Rep. 2018 Mar 26;8(1):5171. doi: 10.1038/s41598-018-23554-5.
本文引用的文献
1
Processing of X-ray diffraction data collected in oscillation mode.振荡模式下收集的X射线衍射数据的处理。
Methods Enzymol. 1997;276:307-26. doi: 10.1016/S0076-6879(97)76066-X.
2
Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12.心脏保护趋化因子SDF-1/CXCL12的单体结构
Protein Sci. 2009 Jul;18(7):1359-69. doi: 10.1002/pro.167.
3
Phaser crystallographic software.相位结晶学软件。
J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674. doi: 10.1107/S0021889807021206. Epub 2007 Jul 13.
4
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12.趋化因子SDF-1/CXCL12对CXCR4磺基酪氨酸的识别的结构基础
Sci Signal. 2008 Sep 16;1(37):ra4. doi: 10.1126/scisignal.1160755.
5
Automated structure solution with the PHENIX suite.使用PHENIX套件进行自动化结构解析。
Methods Mol Biol. 2008;426:419-35. doi: 10.1007/978-1-60327-058-8_28.
6
Interconversion between two unrelated protein folds in the lymphotactin native state.淋巴趋化因子天然状态下两种不相关蛋白质折叠之间的相互转换。
Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5057-62. doi: 10.1073/pnas.0709518105. Epub 2008 Mar 25.
7
Chemokines and their receptors: drug targets in immunity and inflammation.趋化因子及其受体：免疫与炎症中的药物靶点
Annu Rev Pharmacol Toxicol. 2008;48:171-97. doi: 10.1146/annurev.pharmtox.48.121806.154841.
8
Inference of macromolecular assemblies from crystalline state.从晶体状态推断大分子组装体
J Mol Biol. 2007 Sep 21;372(3):774-97. doi: 10.1016/j.jmb.2007.05.022. Epub 2007 May 13.
9
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids.MolProbity：蛋白质和核酸的全原子接触与结构验证
Nucleic Acids Res. 2007 Jul;35(Web Server issue):W375-83. doi: 10.1093/nar/gkm216. Epub 2007 Apr 22.
10
Structural and functional basis of CXCL12 (stromal cell-derived factor-1 alpha) binding to heparin.CXCL12（基质细胞衍生因子-1α）与肝素结合的结构和功能基础。
J Biol Chem. 2007 Mar 30;282(13):10018-10027. doi: 10.1074/jbc.M608796200. Epub 2007 Jan 29.
Zotero 插件