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从剂量反应的角度来看,大学生饮酒与相关问题。

A dose-response perspective on college drinking and related problems.

机构信息

Prevention Research Center, 1995 UniversityAvenue, Suite 450, Berkeley, CA94704, USA.

出版信息

Addiction. 2010 Feb;105(2):257-69. doi: 10.1111/j.1360-0443.2009.02767.x.

Abstract

AIMS

In order to examine the degree to which heavy drinking contributes to risks for problems among college drinkers this paper develops and tests a dose-response model of alcohol use that relates frequencies of drinking specific quantities of alcohol to the incidence of drinking problems.

METHODS

A mathematical model was developed that enabled estimation of dose-response relationships between drinking quantities and drinking problems using self-report data from 8698 college drinkers across 14 campuses in California, USA. The model assumes that drinking risks are a direct monotone function of the amount consumed per day and additive across drinking days. Drinking problems accumulate across drinking occasions and are the basis for cumulative reports of drinking problems reported by college drinkers.

RESULTS

Statistical analyses using the model showed that drinking problems were related to every drinking level, but increased fivefold at three drinks and more gradually thereafter. Problems were associated most strongly with occasions on which three drinks were consumed, and more than half of all reported problems were related to occasions on which four or fewer drinks were consumed. There were some important differences in dose-responsiveness between men and women and between different groups of 'light', 'moderate' and 'heavier' drinkers.

CONCLUSION

Many problems among college students are associated with drinking relatively small amounts of alcohol (two to four drinks). Programs to reduce college drinking problems should emphasize risks associated with low drinking levels.

摘要

目的

为了研究大量饮酒对大学生饮酒者出现问题的风险程度,本文开发并测试了一个酒精使用的剂量-反应模型,该模型将特定饮酒量的饮酒频率与饮酒问题的发生率联系起来。

方法

使用来自美国加利福尼亚州 14 个校区的 8698 名大学生的自我报告数据,开发了一个数学模型,以估计饮酒量和饮酒问题之间的剂量-反应关系。该模型假设饮酒风险是消耗酒精量的直接单调函数,并且在饮酒天数上是相加的。饮酒问题在饮酒场合中积累,并作为大学生报告的累积饮酒问题的基础。

结果

使用该模型进行的统计分析表明,饮酒问题与每个饮酒水平都有关,但在三杯及以上时增加了五倍,此后逐渐增加。问题与饮用三杯酒的场合最密切相关,超过一半的报告问题与饮用四杯或更少酒的场合有关。男性和女性以及“轻度”、“中度”和“重度”饮酒者之间的剂量反应性存在一些重要差异。

结论

许多大学生的问题与饮用相对少量的酒精(两到四杯)有关。减少大学生饮酒问题的项目应强调与低饮酒水平相关的风险。

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