从牛分枝杆菌 BCG Tokyo 172（SMP-105）细胞壁骨架（CWS）中分离和鉴定阿拉伯糖霉醇。
Isolation and identification of arabinose mycolates of Cell Wall Skeleton (CWS) derived from Mycobacterium bovis BCG Tokyo 172 (SMP-105).
机构信息
Technology Research & Development Division, Dainippon Sumitomo Pharma Co., Ltd., Konohana-ku, Osaka 554-0022, Japan.
出版信息
J Microbiol Methods. 2010 Mar;80(3):302-5. doi: 10.1016/j.mimet.2010.01.003. Epub 2010 Jan 15.
PMID:20079769
Abstract
A unique hydrolysis method using a two-layer solution, consisting of diluted hydrochloric acid and toluene was developed to isolate whole arabinose mycolates from the cell wall skeleton of Mycobacterium bovis BCG Tokyo 172 (SMP-105) in order to reveal its pivotal role in enhancing immune responses against tumors.
摘要
开发了一种独特的水解方法，使用两层溶液，包括稀盐酸和甲苯，从牛分枝杆菌东京 172 株（SMP-105）细胞壁骨架中分离完整的阿拉伯糖-mycolates，以揭示其在增强抗肿瘤免疫反应中的关键作用。
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