Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
Microbes Infect. 2010 Apr;12(4):280-6. doi: 10.1016/j.micinf.2010.01.001. Epub 2010 Jan 15.
The continuous threat of influenza pandemics determines the urgency and necessity to develop safe and effective vaccines against divergent influenza viruses. This review describes the advancements in the research and development of universal influenza vaccines based on the relatively conserved sequences of M2e, HA, and other proteins of influenza viruses.
流感大流行的持续威胁决定了开发针对不同流感病毒的安全有效的疫苗的紧迫性和必要性。本文综述了基于流感病毒 M2e、HA 和其他蛋白的相对保守序列的通用流感疫苗的研究进展。
