Department of Psychiatry, Brigham and Women's Hospital, Boston, MA 02115, United States.
Psychiatry Res. 2010 Mar 30;176(1):34-9. doi: 10.1016/j.psychres.2008.11.006. Epub 2010 Jan 15.
The objective of the study was to evaluate relationships between sleep habits and depressive symptoms. Pilot study data were collected about sleep schedules, related factors and depression in female college students to find whether their sleep schedules correlate with affective symptoms. In the subsequent main study, similar information was collected under more controlled conditions. Depression was measured using the CES-D (Center for Epidemiologic Studies Depression Scale) and HAM-D-3 (modified Hamilton Depression Rating Scale). Response rates were 31.3% of eligible students for the pilot survey and 71.6% for the main study. Both studies showed that about 20% of students reported weekday sleep debts of greater than 2 h and about 28% reported significantly greater sleep debt and had significantly higher depression scores (P<0.0001) than other students. Melancholic symptoms indicated by high CES-D scores (>24), were observed in 24% of students. Sleep problems explained 13% of the variance for both the CESD scale and the HAM-D-3 scale. Among female college students, those who report a sleep debt of at least 2 h or significant daytime sleepiness have a higher risk of reporting melancholic symptoms than others.
本研究旨在评估睡眠习惯与抑郁症状之间的关系。通过对女大学生的睡眠时间表、相关因素和抑郁情况进行初步研究，以了解她们的睡眠模式是否与情感症状相关。在随后的主要研究中，在更受控的条件下收集了类似的信息。采用 CES-D（流行病学研究中心抑郁量表）和 HAM-D-3（改良汉密尔顿抑郁评定量表）来衡量抑郁程度。符合条件的学生中，参与初步调查的学生的应答率为 31.3%，参与主要研究的学生的应答率为 71.6%。两项研究均表明，约 20%的学生报告工作日睡眠债务超过 2 小时，约 28%的学生报告睡眠债务显著增加，抑郁评分显著升高（P<0.0001）。约 24%的学生出现 CES-D 评分（>24）较高的忧郁症状。睡眠问题可解释 CESD 量表和 HAM-D-3 量表 13%的变异。在女大学生中，报告至少 2 小时睡眠债务或明显日间嗜睡的学生报告忧郁症状的风险高于其他学生。
