巴雷特食管的历史、分子机制和内镜治疗。
History, molecular mechanisms, and endoscopic treatment of Barrett's esophagus.
机构信息
VA North Texas Healthcare System and The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
出版信息
Gastroenterology. 2010 Mar;138(3):854-69. doi: 10.1053/j.gastro.2010.01.002. Epub 2010 Jan 18.
Abstract
This report is an adjunct to the American Gastroenterological Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future. Those documents will consider a number of broad questions on the diagnosis, clinical features, and management of patients with Barrett's esophagus, and the reader is referred to the technical review for an in-depth discussion of those topics. In this report, we review historical, molecular, and endoscopic therapeutic aspects of Barrett's esophagus that are of interest to clinicians and researchers.
摘要
本报告是美国胃肠病学协会研究所关于 Barrett 食管管理的医学立场声明和技术审查的补充，该声明和技术审查将在不久后发表。这些文件将考虑一些关于 Barrett 食管患者的诊断、临床特征和管理的广泛问题，读者可参考技术审查以深入讨论这些主题。在本报告中，我们回顾了 Barrett 食管的历史、分子和内镜治疗方面，这些方面对临床医生和研究人员都很有兴趣。
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本文引用的文献
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In benign Barrett's epithelial cells, acid exposure generates reactive oxygen species that cause DNA double-strand breaks.在良性巴雷特上皮细胞中，酸暴露会产生活性氧，从而导致DNA双链断裂。
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Endoscopic and surgical treatment of mucosal (T1a) esophageal adenocarcinoma in Barrett's esophagus.巴雷特食管黏膜（T1a）期食管腺癌的内镜及手术治疗
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Safety, tolerability, and efficacy of endoscopic low-pressure liquid nitrogen spray cryotherapy in the esophagus.内镜下低压液氮喷雾冷冻疗法治疗食管安全性、耐受性和疗效。
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Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia.含肿瘤的Barrett食管经射频消融后新生鳞状上皮的特性。
Am J Gastroenterol. 2009 Jun;104(6):1366-73. doi: 10.1038/ajg.2009.88. Epub 2009 Apr 21.
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Radiofrequency ablation in Barrett's esophagus with dysplasia.巴雷特食管伴发育异常的射频消融术。
N Engl J Med. 2009 May 28;360(22):2277-88. doi: 10.1056/NEJMoa0808145.
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The Society of Thoracic Surgeons practice guideline series: guidelines for the management of Barrett's esophagus with high-grade dysplasia.胸外科医师协会实践指南系列：巴雷特食管伴高级别异型增生的管理指南
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Radiofrequency ablation of Barrett's esophagus: should everybody get it?巴雷特食管的射频消融术：每个人都应该接受吗？
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Intestinal differentiation in metaplastic, nongoblet columnar epithelium in the esophagus.食管化生无杯状细胞柱状上皮中的肠分化。
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