荠（十字花科）中含有新型长链碱基的神经酰胺糖苷。

Glycocerebroside bearing a novel long-chain base from Sagina japonica (Caryophyllaceae).

机构信息

School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210014 Jiangsu, China.

出版信息

Fitoterapia. 2010 Sep;81(6):540-5. doi: 10.1016/j.fitote.2010.01.015. Epub 2010 Jan 18.

DOI:10.1016/j.fitote.2010.01.015

PMID:20080159

Abstract

A new glycocerebroside (1), along with one reported one (2), was isolated from the ethanol extract of Sagina japonica (Caryophyllaceae) and was fully characterized. The structures of two compounds were identified as (2S, 3S, 4R, 8E)-1-(beta-D-glucopyranosyl-3, 4-dihydroxy-2-[(R)-2'- hydroxypalmitoyl]amino-8-heptadecaene (1) and (2S, 3R, 8E)-1-(beta-D-glucopyranosyl-3-hydroxy-2-[(R)-2'-hydroxypalmitoyl]amino-8-octadecaene (2) by using spectroscopic methods ((1)H, (13)C, and 2D NMR, MS) and chemical degradation.

摘要

从荠（十字花科）的乙醇提取物中分离得到一个新的糖脂（1）和一个已报道的糖脂（2），并对其进行了充分的表征。两种化合物的结构被鉴定为（2S, 3S, 4R, 8E）-1-（β-D-吡喃葡萄糖基-3,4-二羟基-2-[(R)-2'-羟基棕榈酰基]氨基-8-十七碳烯（1）和（2S, 3R, 8E）-1-（β-D-吡喃葡萄糖基-3-羟基-2-[(R)-2'-羟基棕榈酰基]氨基-8-十八碳烯（2），方法是使用光谱方法（1H、13C 和 2D NMR、MS）和化学降解。