打破平衡：肌肉与脂肪的较量。
Tipping the scale: muscle versus fat.
机构信息
Section of Comparative Medicine, Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06520, USA.
出版信息
Nat Cell Biol. 2010 Feb;12(2):102-4. doi: 10.1038/ncb0210-102. Epub 2010 Jan 17.
PMID:20081844
Abstract
Adipocytes and scar tissue form during skeletal muscle degeneration. Two new studies reveal that adipocytes and fibroblasts in skeletal muscle derive from a population of bipotent progenitors that reside within muscle, but are not derived from the muscle lineage. These progenitor cells also have a surprising role in stimulating the restoration of muscle mass during regeneration.
摘要
脂肪细胞和疤痕组织在骨骼肌退化过程中形成。两项新研究揭示，骨骼肌中的脂肪细胞和成纤维细胞来源于存在于肌肉中的多能祖细胞，而不是来源于肌肉谱系。这些祖细胞在刺激肌肉再生过程中恢复肌肉质量方面也起着令人惊讶的作用。
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