Faculdades Pequeno Príncipe (FPP), Curitiba, Paraná, Brazil.
Parasitol Res. 2010 Feb;106(3):661-5. doi: 10.1007/s00436-009-1716-2.
During 15 months (01 April 2003-31 July 2004), 20,389 women showing positive pregnancy tests were included in a serological evaluation of toxoplasmosis prevalence using automated immunoenzymatic assays. The women's serum samples were tested for the presence of IgG and/or IgM antibodies. Overall, 53.03% of the women were positive for IgG and 3.26% were positive for IgM; the analysis used a chi-square adherence test and a significance level of 0.05 (chi(2)=14,720.35; p=0.00). To discriminate between recent and past infection, IgG avidity tests (n=166) were carried out, of which 28.3% (n=47) presented low avidity. The seroconversion index observed in this study was 0.44%. The seroprevalence results obtained were similar to other serology data found in other regions of Brazil. These data demonstrate the importance of continuous regional and national seroepidemiological inquiries to define public health strategies that can revert and reduce serological prevalence, as described in other countries where toxoplasmosis monitoring is mandatory.
在 15 个月（2003 年 4 月 1 日至 2004 年 7 月 31 日）期间，20389 名出现阳性妊娠测试的妇女参加了一项血清学评价，以评估弓形虫病的流行率，采用的是自动化免疫酶联测定法。对这些妇女的血清样本进行 IgG 和/或 IgM 抗体检测。总的来说，53.03%的妇女 IgG 呈阳性，3.26%的妇女 IgM 呈阳性；分析采用卡方拟合优度检验，显著性水平为 0.05（卡方值=14720.35；p=0.00）。为了区分近期和既往感染，对 IgG 亲和力测试（n=166）进行了分析，其中 28.3%（n=47）表现出低亲和力。本研究中观察到的血清转化率指数为 0.44%。本研究中获得的血清流行率结果与巴西其他地区的其他血清学数据相似。这些数据表明，需要不断进行区域和国家血清流行病学调查，以制定公共卫生策略，来改变和降低血清流行率，就像在其他国家一样，那里的弓形虫病监测是强制性的。
