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Fine-tuning silencing.
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Jarid2 and PRC2, partners in regulating gene expression.
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A novel form of JARID2 is required for differentiation in lineage-committed cells.
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Polycomb recruitment at the Class II transactivator gene.
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JARID2 and the PRC2 complex regulate the cell cycle in skeletal muscle.
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Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.
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Two Functional Axes of Feedback-Enforced PRC2 Recruitment in Mouse Embryonic Stem Cells.
Stem Cell Reports. 2020 Dec 8;15(6):1287-1300. doi: 10.1016/j.stemcr.2020.07.007. Epub 2020 Aug 6.
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JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.
Nature. 2010 Mar 11;464(7286):306-10. doi: 10.1038/nature08788.

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A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo.
PLoS One. 2012;7(11):e49435. doi: 10.1371/journal.pone.0049435. Epub 2012 Nov 20.
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Inactive yet indispensable: the tale of Jarid2.
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1
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.
Cell. 2009 Dec 24;139(7):1303-14. doi: 10.1016/j.cell.2009.12.003.
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Mechanisms of polycomb gene silencing: knowns and unknowns.
Nat Rev Mol Cell Biol. 2009 Oct;10(10):697-708. doi: 10.1038/nrm2763. Epub 2009 Sep 9.
5
Mechanisms involved in the regulation of histone lysine demethylases.
Curr Opin Cell Biol. 2008 Jun;20(3):316-25. doi: 10.1016/j.ceb.2008.03.004. Epub 2008 Apr 25.
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Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency.
Stem Cells. 2008 Jun;26(6):1496-505. doi: 10.1634/stemcells.2008-0102. Epub 2008 Apr 10.
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H3K27 demethylases, at long last.
Cell. 2007 Oct 5;131(1):29-32. doi: 10.1016/j.cell.2007.09.026.
8
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes.
EMBO J. 2007 Sep 19;26(18):4078-88. doi: 10.1038/sj.emboj.7601837. Epub 2007 Aug 30.
9
The polycomb group protein Suz12 is required for embryonic stem cell differentiation.
Mol Cell Biol. 2007 May;27(10):3769-79. doi: 10.1128/MCB.01432-06. Epub 2007 Mar 5.
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A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Cell. 2006 Apr 21;125(2):315-26. doi: 10.1016/j.cell.2006.02.041.

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