Kuzela S, Kolarov J, Krempaský V, Hatalová I, Lakota J, Ujházy V
Neoplasma. 1977;24(5):559-62.
The specific activity and the content of ATPase in mitochondria of rat liver and Zajdela hepatoma were compared. The specific activity of ATPase in sonicated mitochondria and in mitochondrial membrane fraction of rat liver was almost two times higher than the specific activity in the corresponding fraction of Zajdela hepatoma. Accordingly, the autovertin binding capacity of rat liver mitochondrial membrane fraction as well as the yield of F1-ATPase from this fraction were about two times higher than those of the mitochondrial membrane fraction of Zajdela hepatoma. The results show that mitochondria of Zajdela Hapatoma possess about half amount of ATPase present in rat liver mitochondria.
比较了大鼠肝脏和Zajdela肝癌线粒体中ATP酶的比活性和含量。大鼠肝脏超声处理线粒体和线粒体膜部分中ATP酶的比活性几乎比Zajdela肝癌相应部分的比活性高两倍。因此,大鼠肝脏线粒体膜部分的自稳素结合能力以及该部分F1-ATP酶的产量比Zajdela肝癌线粒体膜部分高约两倍。结果表明,Zajdela肝癌线粒体中ATP酶的含量约为大鼠肝脏线粒体的一半。