Sponheim E
Barnepsykiatrisk Klinikk ved Universitetet i Oslo.
Tidsskr Nor Laegeforen. 1991 Feb 28;111(6):704-7.
It has been postulated that there may be a connection between wheat-gluten/milk-casein and mental disorders such as schizophrenia, hyperactivity and autism. In this study seven patients with infantile autism, three before puberty and four after puberty, were given a gluten-free diet. Three children were provoked with gluten/placebo in a double-blind study. Four young patients participated in an open study and were given a gluten-free diet in six months. Behaviour was registered before, during and after the period with a gluten-free diet. Visual Analogue Scale and Real Life Rating Scale were used to register changes in behaviour. No connection was observed between gluten and behaviour typical for these patients. On the contrary, the gluten-free diet seemed to be another negative factor leading to further social isolation in this group of highly socially handicapped patients and families.
据推测，小麦麸质/牛奶酪蛋白与精神障碍如精神分裂症、多动和自闭症之间可能存在联系。在本研究中，七名患有婴儿自闭症的患者，三名青春期前和四名青春期后，接受了无麸质饮食。在一项双盲研究中，三名儿童用麸质/安慰剂激发。四名年轻患者参与了一项开放性研究，并在六个月内接受了无麸质饮食。在无麸质饮食期间之前、期间和之后记录行为。使用视觉模拟量表和现实生活评定量表来记录行为变化。未观察到麸质与这些患者典型行为之间的联系。相反，无麸质饮食似乎是导致这组社会功能严重受损的患者和家庭进一步社会隔离的另一个负面因素。
