Moore Robert D, Beyer Roger D, Jacoby Karny, Freedman Sheldon J, McCammon Kurt A, Gambla Mike T
Advanced Pelvic Surgery and Urogynecology, Atlanta Urogynecology Associates, Atlanta, GA 30005, USA.
Int Urogynecol J. 2010 May;21(5):545-52. doi: 10.1007/s00192-009-1071-y. Epub 2010 Jan 20.
Two-year outcomes of treating cystocele with a polypropylene mesh (Perigee System with IntePro, AMS, Inc.) placed via a transobturator approach are reported.
A prospective, multicenter trial was conducted evaluating 114 women with >or= stage II anterior wall prolapse defined using International Continence Society guidelines. Treatment success was defined as anterior stage <or= I at a 24-month follow-up. Quality of life questionnaires were administered at baseline and follow-up. Complications were reported via adverse events.
Efficacy at 24 months was 88.5% (77/87). Pelvic floor distress inventory, pelvic floor impact questionnaire-7, and pelvic organ prolapse/urinary incontinence sexual questionnaire were all significantly improved from baseline (p < 0.001). Complication rates reported were vaginal mesh extrusion 10.5% (12/114) and groin, pelvic, or vaginal pain 4.4% (5/114). Six subjects reported de novo dyspareunia. Out of the 49 subjects reporting dyspareunia at baseline, 15 were resolved postoperatively.
The Perigee System is an effective treatment to repair anterior wall prolapse with a low rate of complications through a 2-year follow-up.
