Faculty of Medicine, Social Epidemiology, Lund University, Malmö, Sweden.
Pharmacoepidemiol Drug Saf. 2010 Apr;19(4):358-66. doi: 10.1002/pds.1917.
To investigate the association between socioeconomic position and use of lipid-lowering drugs and ACE-inhibitors after an acute myocardial infarction (AMI) when simultaneously considering participation in the national quality register RIKS-HIA (Register of Information and Knowledge about Swedish Heart Intensive care Admissions), age, sex and previous hospitalizations of the patients.
Population-based prospective cohort study included all 1346 AMI patients cared in the county of Scania, Sweden during 2006 of whom 1061 were register at the RIKS-HIA. Treatment with lipid-lowering and ACE-inhibiting therapy in relation to income was investigated with Cox and logistic regression modelling.
In the whole population of AMI patients, high income patients had a higher adherence to guidelines for pharmacological secondary prevention than low income patients (HR(lipid-lowering drug): 1.29; 95%CI: 1.12-1.49 and HR(ACE-inhibitor therapy): 1.22; 95%CI: 1.04-1.43). Among RIKS-HIA participants, patients with high income presented a better adherence to lipid-lowering treatment than patients with low income (HR: 1.15; 95%CI: 0.98-1.34).
Our investigation reveals that the Swedish goal of access to health care on equal terms and according to needs is still not fully accomplished. Moreover, since this pattern of inequity in pharmacological secondary prevention may lead to the recurrence of heart disease, these inequities are not only a matter of fairness and social justice, but also a potential (and modifiable) source of ineffectiveness and inefficiency in health care.
当同时考虑患者参与国家质量登记 RIKS-HIA(瑞典心脏重症监护入院信息和知识登记)、年龄、性别和既往住院情况时,调查社会经济地位与急性心肌梗死(AMI)后使用降脂药和 ACE 抑制剂之间的关系。
本研究为基于人群的前瞻性队列研究,纳入了 2006 年在瑞典斯科讷县接受治疗的所有 1346 例 AMI 患者,其中 1061 例在 RIKS-HIA 登记。使用 Cox 和逻辑回归模型研究了收入与降脂和 ACE 抑制剂治疗之间的关系。
在所有 AMI 患者人群中,高收入患者接受药物二级预防的依从性高于低收入患者(降脂药物的 HR:1.29;95%CI:1.12-1.49 和 ACE 抑制剂治疗的 HR:1.22;95%CI:1.04-1.43)。在 RIKS-HIA 参与者中,高收入患者的降脂治疗依从性优于低收入患者(HR:1.15;95%CI:0.98-1.34)。
我们的研究表明,瑞典实现平等获得医疗保健和按需提供医疗保健的目标尚未完全实现。此外,由于这种药物二级预防方面的不平等模式可能导致心脏病再次发作,因此这些不平等不仅是公平和社会正义的问题,而且是医疗保健无效和低效的潜在(和可改变)来源。