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实时动态多叶准直器跟踪技术在逆向优化弧形放疗中的应用。

Real-time dynamic MLC tracking for inversely optimized arc radiotherapy.

机构信息

Department of Radiation Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.

出版信息

Radiother Oncol. 2010 Feb;94(2):218-23. doi: 10.1016/j.radonc.2009.12.022. Epub 2010 Jan 19.

Abstract

BACKGROUND AND PURPOSE

Motion compensation with MLC tracking was tested for inversely optimized arc radiotherapy with special attention to the impact of the size of the target displacements and the angle of the leaf trajectory.

MATERIALS AND METHODS

An MLC-tracking algorithm was used to adjust the MLC positions according to the target movements using information from an optical real-time positioning management system. Two plans with collimator angles of 45 degrees and 90 degrees , respectively, were delivered and measured using the Delta(4)(R) dosimetric device moving in the superior-inferior direction with peak-to-peak displacements of 5, 10, 15, 20 and 25 mm and a cycle time of 6s.

RESULTS

Gamma index evaluation for plan delivery with MLC tracking gave a pass rate higher than 98% for criteria 3% and 3 mm for both plans and for all sizes of the target displacement. With no motion compensation, the average pass rate was 75% for plan 1 and 70% for plan 2 for 25 mm peak-to-peak displacement.

CONCLUSION

MLC tracking improves the accuracy of inversely optimized arc delivery for the cases studied. With MLC tracking, the dosimetric accuracy was independent of the magnitude of the peak-to-peak displacement of the target and not significantly affected by the angle between the leaf trajectory and the target movements.

摘要

背景与目的

本文研究了逆向优化弧形放射治疗中使用多叶准直器(MLC)跟踪的运动补偿,特别关注目标位移大小和叶片轨迹角度的影响。

材料与方法

使用基于光学实时定位管理系统的信息,通过 MLC 跟踪算法根据目标运动调整 MLC 位置。使用 Delta(4)(R)剂量计,在上下方向上以 5、10、15、20 和 25mm 的峰峰值位移和 6s 的周期时间进行测量,分别传输具有 45 度和 90 度准直器角度的两个计划。

结果

对于具有 MLC 跟踪的计划传输,伽马指数评估的通过率高于 98%,符合 3%和 3mm 的标准,对于所有目标位移大小都是如此。没有运动补偿时,对于 25mm 的峰峰值位移,计划 1 的平均通过率为 75%,计划 2 的平均通过率为 70%。

结论

在研究案例中,MLC 跟踪提高了逆向优化弧形传输的准确性。使用 MLC 跟踪时,剂量学准确性与目标的峰峰值位移大小无关,并且不受叶片轨迹与目标运动之间角度的显著影响。

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