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拉各斯蝙蝠病毒在尼日利亚果蝠中传播的证据。

Evidence of Lagos bat virus circulation among Nigerian fruit bats.

作者信息

Dzikwi Asabe A, Kuzmin Ivan I, Umoh Jarlath U, Kwaga Jacob K P, Ahmad Aliyu A, Rupprecht Charles E

机构信息

Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria 810107, Nigeria.

出版信息

J Wildl Dis. 2010 Jan;46(1):267-71. doi: 10.7589/0090-3558-46.1.267.

DOI:10.7589/0090-3558-46.1.267
PMID:20090042
Abstract

During lyssavirus surveillance, 350 brains from four species of fruit bats and one species of insectivorous bat were collected from seven locations in Northern Nigeria during May to October, 2006. Lyssavirus antigen was not detected in the brains, and isolation attempts in mice were unsuccessful. However, serologic tests demonstrated the presence of lyssavirus-neutralizing antibodies in bat sera. Of 140 sera tested, 27 (19%) neutralized Lagos bat virus, and two of these additionally neutralized Mokola virus. The positive samples originated from the straw-colored fruit bat (Eidolon helvum) and the Gambian epaulet bat (Epomophorus gambianus). No neutralizing activity was detected against other lyssaviruses including rabies, Duvenhage, and West Caucasian bat viruses.

摘要

在2006年5月至10月期间,于尼日利亚北部的七个地点采集了来自四种果蝠和一种食虫蝙蝠的350个脑样本。在这些脑中未检测到狂犬病病毒抗原,并且在小鼠身上进行的分离尝试未成功。然而,血清学检测表明蝙蝠血清中存在狂犬病病毒中和抗体。在检测的140份血清中,27份(19%)中和了拉各斯蝙蝠病毒,其中两份还额外中和了莫科拉病毒。阳性样本来自淡黄果蝠(锤头果蝠)和冈比亚肩章果蝠。未检测到针对其他狂犬病病毒(包括狂犬病病毒、杜文海格病毒和西高加索蝙蝠病毒)的中和活性。

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