Qazi Yureeda, Maddula Surekha, Ambati Balamurali K
Department of Ophthalmology, John Moran Eye Center, University of Utah, Salt Lake City, UT-84132, USA.
J Genet. 2009 Dec;88(4):495-515. doi: 10.1007/s12041-009-0068-0.
Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade.
血管生成是指从已有的脉管系统形成新的血管。眼部的病理性血管生成会导致严重的视力损害。在我们的综述中，我们讨论了促血管生成和抗血管生成分子在角膜血管生成、增殖性糖尿病视网膜病变、渗出性黄斑变性和早产儿视网膜病变中的作用，重点介绍了过去十年中出现的新靶点。
