Dall J L
University of Glasgow, UK.
Cardiovasc Drugs Ther. 1991 Jan;4 Suppl 6:1263-8. doi: 10.1007/BF00114231.
Cardiovascular diseases are of fundamental importance in the cause of death and morbidity in the elderly as a group. If the successful management of blood pressure can effect a reduction in morbid events as well as death, as has been indicated by recent trials, the elderly have more to gain than any other group within the population by adequate treatment of blood pressure. The physiologic response to aging in the cardiovascular system has characteristics similar to a beta-adrenergic blocking effect. Some similar changes are seen in older hypertensives. Hypertension may represent premature aging in the cardiovascular system. Blood pressure can be reduced in elderly people, and it is now relevant to determine whether one particular method of reducing blood pressure has advantages over others. Education of the elderly as to the advantages of treatment is important, but education of professionals who prescribe is, perhaps, more important. A clear understanding of the gains to be made and the side effects of different groups of drugs is necessary to allow the doctor to prescribe confidently for the elderly patient.
心血管疾病在老年人群体的死因和发病率中至关重要。如果正如近期试验所表明的那样，成功控制血压能够降低发病事件以及死亡率，那么通过充分治疗血压，老年人比人群中的任何其他群体都能获得更多益处。心血管系统对衰老的生理反应具有类似于β-肾上腺素能阻滞效应的特征。在老年高血压患者中也可见到一些类似的变化。高血压可能代表心血管系统的过早衰老。老年人的血压是可以降低的，现在有必要确定一种特定的降压方法是否比其他方法更具优势。对老年人进行治疗益处的教育很重要，但对开处方的专业人员进行教育或许更为重要。医生要能自信地为老年患者开处方，就必须清楚了解不同类别药物的益处和副作用。
