Cray Carolyn, Watson Toshiba, Arheart Kristopher L
University of Miami Miller School of Medicine, Division of Comparative Pathology, P.O. Box 016960 R-46, Miami, FL 33101, USA.
Avian Dis. 2009 Dec;53(4):491-4. doi: 10.1637/8673-030209-Reg.1.
A multiyear study was conducted using an enzyme-linked immunosorbent assay to measure antibody to address the application of the test to the diagnosis of aspergillosis in avian species. In general serostudies (n=1314), four avian groups (psittaciform, raptor, penguin, and zoo) were found to have samples with antibody reactivity. Penguin, raptor, and zoo groups were found to have higher levels of antibody to Aspergillus than the psittaciform group. Additional clinical information was collected on 303 cases, which resulted in the definition of presumptive normal, probable, and confirmed infection groups. Although the confirmed group was more likely to have antibody reactivity, the mean antibody index was not found to be significant between presumptive normal and probable or confirmed cases.
进行了一项为期多年的研究，使用酶联免疫吸附测定法来检测抗体，以探讨该检测方法在鸟类曲霉菌病诊断中的应用。在一般血清学研究（n = 1314）中，发现四个鸟类群体（鹦鹉形目、猛禽、企鹅和动物园鸟类）的样本具有抗体反应性。发现企鹅、猛禽和动物园鸟类群体对曲霉菌的抗体水平高于鹦鹉形目群体。收集了303例病例的额外临床信息，从而确定了推定正常、可能和确诊感染组。虽然确诊组更有可能具有抗体反应性，但在推定正常与可能或确诊病例之间，平均抗体指数并无显著差异。
